Evidence map›Paper›PMID 32068459›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats.

Kasi C McPherson, Corbin A Shields, Bibek Poudel, Ashley C Johnson, Lateia Taylor, Cassandra Stubbs, Alyssa Nichols, Denise C Cornelius, Michael R Garrett, Jan M Williams

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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  8. Neutralizing MIP3The Journal of pharmacology and experimental therapeutics · 2023
    Article
  9. Review
  10. An American Physiological Society cross-journal Call for Papers on "The Physiology of Obesity".American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  11. The SSAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  12. Article
  13. Increased Levels of Renal Lysophosphatidic Acid in Rodent Models with Renal Disease.The Journal of pharmacology and experimental therapeutics · 2021
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kasi C McPhersonDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Corbin A ShieldsDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Bibek PoudelDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Ashley C JohnsonDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Lateia TaylorDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Cassandra StubbsDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Alyssa NicholsDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Denise C CorneliusDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.ORCID 0000-0002-6730-6499
Michael R GarrettDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Jan M WilliamsDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
University of Mississippi Medical Center · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI Vijay Rangachari · 2012 to 2026
$60.2M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Babbette LaMarca, Jane F Reckelhoff · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
Mechanisms involved in the early development of renal disease associated with prepubertal obesityR01DK109133 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI WILLIAMS, JAN MICHAEL · 2017 to 2021
$1.7M
Genetic Targets of Hypertension End Organ DamageR01HL137673 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI GARRETT, MICHAEL R · 2018 to 2021
$1.6M
Hypertension and InflammationR00HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2017 to 2019
$747k
Hypertension and InflammationK99HL130456 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2016 to 2016
$136k
The role of ET-1 in lipid accumulation during the development of glomerular injury associated with MetSF31DK109571 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI MCPHERSON, KASI C · 2016 to 2016
$26k
NHLBI NIH HHS K99 HL130456NHLBI NIH HHS R00 HL130456NHLBI NIH HHS R01 HL137673NIDDK NIH HHS F31 DK109571NIDDK NIH HHS R01 DK109133NIGMS NIH HHS P20 GM103476NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

The present study examined whether development of renal injury in the nondiabetic obese Dahl salt-sensitive leptin receptor mutant (SS

Indexed as

HemodynamicsLipid MetabolismMutationRenal CirculationAdipose TissueAdiposityAnimalsATP Binding Cassette Transporter 1ATP-Binding Cassette TransportersCD36 AntigensChemokine CXCL16Disease Models, AnimalGenetic Predisposition to DiseaseGlomerular Filtration RateHypertensionKidney DiseasesAbca1 protein, ratAbca2 protein, ratATP Binding Cassette Transporter 1ATP-Binding Cassette TransportersCD36 AntigensCd36 protein, ratChemokine CXCL16Receptors, LeptinSodium Chloride, Dietaryglomerular filtration ratelipid accumulationobesityrenal hyperfiltrationsalt-sensitive ratsSSLepRmutant strain

Identifiers

PMID32068459
PMCPMC7191445
OpenAlexW3007031267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.