Evidence map›Paper›PMID 32068308›Full record

ArticleGlia2020

DNA methylation: A mechanism for sustained alteration of KIR4.1 expression following central nervous system insult.

Jessica L Boni, Uri Kahanovitch, Sinifunanya E Nwaobi, Candace L Floyd, Michelle L Olsen

Open access · greenAbstract read
In one paragraph

Article in Glia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Astrocytic KFrontiers in aging neuroscience · 2026
    Review
  3. Astrocytic transcriptional and epigenetic mechanisms of drug addiction.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Jessica L BoniDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-1219-3682
Uri KahanovitchSchool of Neuroscience, Virginia Polytechnic and State University, Blacksburg, Virginia.ORCID 0000-0002-6203-7103
Sinifunanya E NwaobiDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama.
Candace L FloydDepartment of Physical Medicine and Rehabilitation, University of Alabama at Birmingham, Birmingham, Alabama.
Michelle L OlsenDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-1394-664X
University of Alabama at Birmingham · USUniversity of California, Los Angeles · USUniversity of Utah · USVirginia Tech · US

Funding

Glial chemosensitivity: pH sensing and interactions with neuronal chemoreceptorsR01HL104101 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI MULKEY, DANIEL K, OLSEN, MICHELLE L · 2010 to 2024
$5.5M
Epigenetic Regulation of Kir4.1 and GLT1 in PathophysiologyR01NS075062 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI OLSEN, MICHELLE L · 2013 to 2017
$1.6M
Medical Research Council MC_PC_19026NHLBI NIH HHS R01 HL104101NINDS NIH HHS R01 NS075062
6 · The paper itself

Abstract

Kir4.1, a glial-specific inwardly rectifying potassium channel, is implicated in astrocytic maintenance of K

Indexed as

AnimalsAstrocytesCentral Nervous SystemDNA MethylationEpilepsyKcnj10 ChannelNeurogliaNeuronsPotassium Channels, Inwardly RectifyingRats, Sprague-DawleySeizuresSpinal Cord InjuriesKcnj10 ChannelPotassium Channels, Inwardly RectifyingastrocyteDNA methylationKcnj10Kir4.1Pilocarpine

Identifiers

PMID32068308
PMCPMC8665281
OpenAlexW3007101783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.