Evidence map›Paper›PMID 32067636›Full record

ArticleeLife2020

Genetic analysis of the Arabidopsis TIR1/AFB auxin receptors reveals both overlapping and specialized functions.

Michael J Prigge, Matthieu Platre, Nikita Kadakia, Yi Zhang, Kathleen Greenham, Whitnie Szutu, Bipin Kumar Pandey, Rahul Arvind Bhosale, Malcolm J Bennett, Wolfgang Busch and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
28.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 180 citations in OpenAlex.

  1. Force-responsive symmetric cell divisions orient stomata along global tissue axes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Slow and rapid auxin responses in Arabidopsis.Journal of experimental botany · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Michael J PriggeSection of Cell and Developmental Biology, University of California San Diego, La Jolla, United States.ORCID 0000-0003-0671-2538
Matthieu PlatrePlant Molecular and Cellular Biology Laboratory and Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Nikita KadakiaSection of Cell and Developmental Biology, University of California San Diego, La Jolla, United States.
Yi ZhangSection of Cell and Developmental Biology, University of California San Diego, La Jolla, United States.
Kathleen GreenhamSection of Cell and Developmental Biology, University of California San Diego, La Jolla, United States.ORCID 0000-0001-7681-5263
Whitnie SzutuSection of Cell and Developmental Biology, University of California San Diego, La Jolla, United States.ORCID 0000-0002-2083-7241
Bipin Kumar PandeyPlant and Crop Sciences, School of Biosciences, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0002-9614-1347
Rahul Arvind BhosalePlant and Crop Sciences, School of Biosciences, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0001-6515-4922
Malcolm J BennettPlant and Crop Sciences, School of Biosciences, University of Nottingham, Nottingham, United Kingdom.
Wolfgang BuschPlant Molecular and Cellular Biology Laboratory and Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Mark EstelleSection of Cell and Developmental Biology, University of California San Diego, La Jolla, United States.ORCID 0000-0002-2613-8652
University of California San Diego · USUniversity of Nottingham · GBSalk Institute for Biological Studies · USUniversity of California, Los Angeles · USUniversity of California, Riverside · USUniversity of Minnesota · US

Funding

MOLECULAR GENETICS OF AUXIN ACTION IN ARABIDOPSISR01GM043644 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI ESTELLE, MARK A · 1989 to 2021
$6.0M
Human Frontier Science Program LT000340/2019-LNIGMS NIH HHS R01 GM043644
6 · The paper itself

Abstract

The TIR1/AFB auxin co-receptors mediate diverse responses to the plant hormone auxin. The Arabidopsis genome encodes six TIR1/AFB proteins representing three of the four clades that were established prior to angiosperm radiation. To determine the role of these proteins in plant development we performed an extensive genetic analysis involving the generation and characterization of all possible multiply-mutant lines. We find that loss of all six TIR1/AFB proteins results in early embryo defects and eventually seed abortion, and yet a single wild-type allele of

Indexed as

ArabidopsisArabidopsis ProteinsF-Box ProteinsPlant ProteinsReceptors, Cell SurfaceAFB2 protein, ArabidopsisArabidopsis Proteinsauxin receptor, plantF-Box ProteinsPlant ProteinsReceptors, Cell SurfaceTIR1 protein, ArabidopsisA. thalianaauxindevelopmental biologyplantplant biologyplant developmentplant hormone

Identifiers

PMID32067636
PMCPMC7048394
OpenAlexW3007979892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.