Evidence map›Paper›PMID 32067586›Full record

ArticleJournal of the American Heart Association2020

Xu Yang, Wei Yang, David G McVey, Guojun Zhao, Jinfu Hu, Robin N Poston, Meixia Ren, Karin Willeit, Stefan Coassin, Johann Willeit and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Article
  9. Functional Roles of Furin in Cardio-Cerebrovascular Diseases.ACS pharmacology & translational science · 2024
    Review
  10. Plasma Proteomics to Identify Drug Targets for Ischemic Heart Disease.Journal of the American College of Cardiology · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 4 countries.

Xu YangShantou University Medical College Shantou China.
Wei YangShantou University Medical College Shantou China.
David G McVeyDepartment of Cardiovascular Sciences and National Institute for Health Research Leicester Biomedical Research Centre University of Leicester United Kingdom.
Guojun ZhaoShantou University Medical College Shantou China.
Jinfu HuShantou University Medical College Shantou China.
Robin N PostonWilliam Harvey Research Institute Queen Mary University of London London United Kingdom.
Meixia RenDepartment of Geriatric Medicine Fujian Provincial Hospital Fuzhou China.
Karin WilleitDepartment of Neurology Bern University Hospital University of Bern Switzerland.
Stefan CoassinInstitute of Genetic Epidemiology Medical University of Innsbruck Innsbruck Austria.
Johann WilleitDepartment of Neurology Medical University of Innsbruck Innsbruck Austria.
Thomas R WebbDepartment of Cardiovascular Sciences and National Institute for Health Research Leicester Biomedical Research Centre University of Leicester United Kingdom.
Nilesh J SamaniDepartment of Cardiovascular Sciences and National Institute for Health Research Leicester Biomedical Research Centre University of Leicester United Kingdom.
Manuel MayrCardiovascular Division King's College London London United Kingdom.
Stefan KiechlDepartment of Neurology Medical University of Innsbruck Innsbruck Austria.
Shu YeShantou University Medical College Shantou China.
Universität Innsbruck · ATNational Institute for Health Research · GBFujian Provincial Hospital · CNGuangzhou Medical University · CNKing's College London · GBNIHR Leicester Biomedical Research Centre · GBQueen Mary University of London · GBSecond Affiliated Hospital of Shantou University Medical College · CNShantou University · CNShantou University Medical College · CNUniversity of Bern · CHUniversity of Leicester · GB

Funding

British Heart Foundation CH/16/3/32406British Heart Foundation PG/16/9/31995British Heart Foundation PG/18/73/34059British Heart Foundation RG/16/13/32609British Heart Foundation RG/16/14/32397British Heart Foundation RG/19/9/34655British Heart Foundation SP/16/4/32697British Heart Foundation SP/19/2/344612Department of Health
6 · The paper itself

Abstract

Background Genome-wide association studies have shown an association between the single-nucleotide polymorphism

Indexed as

AdultAgedCarotid Intima-Media ThicknessChemokine CCL2Coronary Artery DiseaseEndothelial CellsEndothelium, VascularFemaleFurinHumansMaleMiddle AgedMonocytesPolymorphism, Single NucleotideTransendothelial and Transepithelial MigrationVascular Cell Adhesion Molecule-1Chemokine CCL2FurinFURIN protein, humanVascular Cell Adhesion Molecule-1coronary artery diseaseendothelial cellsFURINsingle‐nucleotide polymorphism

Identifiers

PMID32067586
PMCPMC7070217
OpenAlexW3005845868

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.