Evidence map›Paper›PMID 32067480›Full record

ArticleCell transplantation

Engineered Stem Cells Improve Neurogenic Bladder by Overexpressing SDF-1 in a Pelvic Nerve Injury Rat Model.

Guan Qun Zhu, Seung Hwan Jeon, Kyu Won Lee, Hyuk Jin Cho, U-Syn Ha, Sung-Hoo Hong, Ji Youl Lee, Eun Bi Kwon, Hyo-Jin Kim, Soon Min Lee and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Guan Qun ZhuDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID 0000-0001-7841-8026
Seung Hwan JeonDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Kyu Won LeeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Hyuk Jin ChoDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
U-Syn HaDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Sung-Hoo HongDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ji Youl LeeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Eun Bi KwonDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Hyo-Jin KimDepartment of Stem Cell Therapy, SL BIGEN, Seongnam, Republic of Korea.
Soon Min LeeDepartment of Stem Cell Therapy, SL BIGEN, Seongnam, Republic of Korea.
Hey-Yon KimDepartment of Stem Cell Therapy, SL BIGEN, Seongnam, Republic of Korea.
Sea Woong KimDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Woong Jin BaeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Catholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is still a lack of sufficient research on the mechanism behind neurogenic bladder (NB) treatment. The aim of this study was to explore the effect of overexpressed stromal cell-derived factor-1 (SDF-1) secreted by engineered immortalized mesenchymal stem cells (imMSCs) on the NB. In this study, primary bone marrow mesenchymal stem cells (BM-MSCs) were transfected into immortalized upregulated SDF-1-engineered BM-MSCs (imMSCs/eSDF-1

Indexed as

AnimalsApoptosisBlotting, WesternChemokine CXCL12Fluorescent Antibody TechniqueMaleMesenchymal Stem CellsPeripheral Nerve InjuriesRatsSignal TransductionUrinary Bladder, NeurogenicChemokine CXCL12CXCL12 protein, ratgene regulationhomingmesenchymal stem cellsneurogenic bladderSDF-1 overexpression

Identifiers

PMID32067480
PMCPMC7444235
OpenAlexW3008021517

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.