Evidence map›Paper›PMID 32067402›Full record

ArticleClinical and experimental dental research2020

Relationship between hypothyroidism and periodontitis: A scoping review.

Hajer A Aldulaijan, Robert E Cohen, Elizabeth M Stellrecht, Michael J Levine, Lisa M Yerke

Abstract readScoping Review
In one paragraph

Article in Clinical and experimental dental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Bidirectional Association between Periodontitis and Thyroid Disease: A Scoping Review.International journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hajer A AldulaijanDepartment of Periodontics and Endodontics, University at Buffalo, State University of New York, School of Dental Medicine, Buffalo, New York.
Robert E CohenDepartment of Periodontics and Endodontics, University at Buffalo, State University of New York, School of Dental Medicine, Buffalo, New York.
Elizabeth M StellrechtDepartment of Periodontics and Endodontics, University at Buffalo, State University of New York, School of Dental Medicine, Buffalo, New York.
Michael J LevineDepartment of Periodontics and Endodontics, University at Buffalo, State University of New York, School of Dental Medicine, Buffalo, New York.
Lisa M YerkeDepartment of Periodontics and Endodontics, University at Buffalo, State University of New York, School of Dental Medicine, Buffalo, New York.ORCID 0000-0001-5272-2580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe objective of this study was to assess the existing literature to determine if a relationship exists between hypothyroidism and periodontitis.

methodsWe used a modified approach to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses by searching five databases in addition to the gray literature. Keywords in the title and abstract fields, as well as subject headings for both periodontal disease and hypothyroidism, were used to search the existing literature for publications relevant to evaluation of the thyroid-periodontitis relationship.

resultsThe authors screened 847 unique publications which, after applying inclusion and exclusion criteria, yielded 29 publications, which were further analyzed for relevance and applicability. Most of the included papers were cross-sectional studies and retrospective chart reviews. Following critical analysis, four publications, including one abstract, were used to further assess the hypothyroid-periodontitis relationship.

conclusionsThere are very few high-quality studies describing the potential association between hypothyroidism and periodontitis. In general, and among the included papers with the fewest confounding factors, a positive relationship between hypothyroidism and periodontitis was found. Further well-controlled, prospective clinical and immunologic studies will be required to confirm that relationship.

Indexed as

CausalityConfounding Factors, EpidemiologicCross-Sectional StudiesHumansHypothyroidismPeriodontitisRetrospective Studieshypothyroidismperiodontitisscoping review

Identifiers

PMID32067402
PMCPMC7025985

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.