Evidence map›Paper›PMID 32067191›Full record

ReviewMolecular diagnosis & therapy2020

Emergence of Circulating MicroRNAs in Breast Cancer as Diagnostic and Therapeutic Efficacy Biomarkers.

Vaishali Aggarwal, Kumari Priyanka, Hardeep Singh Tuli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular diagnosis & therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  4. MicroRNAs as Endocrine Modulators of Breast Cancer.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vaishali AggarwalDepartment of Histopathology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Punjab, 160012, India.
Kumari PriyankaDepartment of Immunopathology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Punjab, 160012, India.
Hardeep Singh TuliDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, 133207, India. hardeep.biotech@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the second most common cause of deaths reported in women worldwide, and therefore there is a need to identify breast cancer patients at an early stage as timely diagnosis would help in effective management and appropriate monitoring of patients. Nevertheless, it is challenging to achieve these goals due to the lack of a specific biomarker for early detection and monitoring in breast cancer. Recently, microRNAs (miRNAs) have emerged as master regulators of the molecular pathways highlighted in different tumors leading to progression in malignancies. With the rapid advancements in molecular research, the potential to use miRNAs as prognostic and diagnostic biomarkers in breast cancer has been highlighted, as their dysregulation is directly associated with breast cancer progression and metastasis. The ease of detection and long-term stability of circulating miRNAs in blood makes them a promising candidate for non-invasive breast cancer biomarkers.

Indexed as

Biomarkers, TumorBreast NeoplasmsCirculating MicroRNADisease ProgressionEarly Detection of CancerFemaleGene Expression Regulation, NeoplasticHumansBiomarkers, TumorCirculating MicroRNA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.