ArticleJapanese journal of radiology2020
A combined DTI and resting state functional MRI study in patients with postherpetic neuralgia.
Article in Japanese journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- A meta-analysis of resting-state fMRI in postherpetic neuralgia using AES-SDM.Frontiers in neuroscience · 2025Pooled it
- Functional connectome gradient alterations in herpes zoster and postherpetic neuralgia: associations with gene expression profiles.The journal of headache and pain · 2026Article
- Structural and Functional Brain Alterations in Postherpetic Neuralgia: A Systematic Review and Voxel-Wise Coordinate-Based Meta-Analysis via the SDM-PSI Method.Journal of pain research · 2026Review
- Multi-network dynamical structure of the human brain in the setting of chronic pain: a coordinate-based meta-analysis.Brain communications · 2025Article
- Combined Functional and Structural Imaging of White Matter Reveals Brain Connectivity Alterations in Fibromyalgia Patients.Journal of pain research · 2025Article
- Altered white matter microstructural integrity in patients with postherpetic neuralgia: a combined DTI and DTI-NODDI study.Frontiers in neuroscience · 2025Article
- Local Structural Indices Changes During Different Periods of Postherpetic Neuralgia: A Graphical Study in Structural Covariance Networks.Journal of pain research · 2025Article
- The "brain-gut" mechanism of postherpetic neuralgia: a mini-review.Frontiers in neurology · 2025Review
- Central effects of short-term spinal cord stimulation in postherpetic neuralgia: a longitudinal fMRI and DTI study.Frontiers in neuroscience · 2025Article
- Investigating the brain functional abnormalities underlying pain hypervigilance in chronic neck and shoulder pain: a resting-state fMRI study.Neuroradiology · 2024Article
- Fractional amplitude of low-frequency fluctuation changes of specific cerebral regions in patients with toothache: A functional magnetic resonance imaging study.Brain and behavior · 2023Article
- Alteration of static and dynamic intrinsic brain activity induced by short-term spinal cord stimulation in postherpetic neuralgia patients.Frontiers in neuroscience · 2023Article
- Altered White Matter Microstructure in Herpes Zoster and Postherpetic Neuralgia Determined by Automated Fiber Quantification.Brain sciences · 2022Article
- Differentiation of Meningiomas and Gliomas by Amide Proton Transfer Imaging: A Preliminary Study of Brain Tumour Infiltration.Frontiers in oncology · 2022Article
- MRI Study of Cerebral Cortical Thickness in Patients with Herpes Zoster and Postherpetic Neuralgia.Journal of pain research · 2022Article
- Alterations in local activity and functional connectivity in patients with postherpetic neuralgia after short-term spinal cord stimulation.Frontiers in molecular neuroscience · 2022Article
- Cerebral structural alterations in the patients undergoing postherpetic neuralgia: A VBM-MRI study.Ibrain · 2022Article
- Diffusion tensor imaging study of the microstructural changes in the white matter of patients with herpes zoster and postherpetic neuralgia.American journal of translational research · 2022Article
- Enhanced Temporal Coupling between Thalamus and Dorsolateral Prefrontal Cortex Mediates Chronic Low Back Pain and Depression.Neural plasticity · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo explore the brain microstructural and functional changes in patients with postherpetic neuralgia (PHN). MATERIALS AND
methods12 PHN patients and 12 healthy volunteers were enrolled. Diffusion tensor imaging (DTI) and resting-state functional MRI (rfMRI) sequences were scanned by a 3T MR scanner. Fractional anisotropy (FA) and mean diffusivity (MD) t-maps were obtained following DTI data processing. The amplitude of low-frequency fluctuation (ALFF) and fractional ALFF (fALFF) were obtained following rfMRI data processing. A two sample t-test was performed to compare the FA, MD, ALFF and fALFF differences between the PHN patients and healthy controls.
resultsNo significant differences were noted with regard to the parameters gender, age and education years between the two groups. FA, MD, ALFF and/or fALFF indicated significant alterations in specific pain or pain-related brain regions, such as brainstem, cerebellum, parietal lobe, precuneus, frontal lobe, temporal lobe, postcentral and precentral gyrus, corpus callosum, cingulate gyrus, putamen and insula.
conclusionMulti-local alterations of spontaneous brain activity could form a network related to chronic pain, sensory discrimination, emotion and cognition, suggesting complicated central mechanisms of PHN. The combined-action of brain microstructure and function may play a critical role in comprehension of neurological mechanisms of PHN-induced pain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.