ArticleNature immunology2020
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
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Article in Nature immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 439 papers.
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0cells of the map it votes in
439citing papers in PubMed
25.8field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
439 citing papers in PubMed, 622 citations in OpenAlex.
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- Compartment-specific PPARδ activity controls the outcome of cancer-immune cell competition and immunotherapy efficacy.Nature immunology · 2026Article
- Metabolic immune checkpoints (MICs) in cancer: from molecular mechanisms to challenges and opportunities in clinical translation.Signal transduction and targeted therapy · 2026Review
- Regulatory T Cells Across Oral Diseases: A Narrative Review on a Functional Perspective.International journal of molecular sciences · 2026Review
- Inhibition of the lipocalin-2-phosphatidylserine axis restores natural killer cell immune surveillance.Cell reports. Medicine · 2026Article
- SREBP1c modulates Treg immunobiology through a phospholipid-dependent adenosine pathway.The Journal of clinical investigation · 2026Article
- Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Fatty Acid Metabolism Rewires Glioblastoma Progression and Treg-Mediated Immune Resistance.Cancers · 2026Review
- Metabolic Bottlenecks and Opportunities: Reshaping the Tumor Microenvironment for Cancer Immunotherapy.Cells · 2026Review
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- The interplay between lipid metabolism, cancer progression and anti-cancer immunity.Experimental & molecular medicine · 2026Review
- Advances in Lipid Metabolism Reprogramming in Hepatocellular Carcinoma.Journal of clinical and translational hepatology · 2026Review
- ASB2 inhibits lipid accumulation to promote ILC1 homeostatic fitness and anti-tumor immunity in the mouse liver.Nature communications · 2026Article
- CD36: bridging metabolism, inflammation, and reproduction.npj metabolic health and disease · 2026Review
- Nrf2-mediated metabolic reprogramming drives regulatory T cell accumulation in hepatocellular carcinoma.Nature communications · 2026Article
- Cancer stem cell plasticity: mechanisms, immune microenvironment crosstalk, and therapeutic implications.Journal of hematology & oncology · 2026Review
- KLF5-driven TAZ-FASN signaling reprograms fatty acid metabolism to support Treg differentiation in lung cancer.Journal of translational medicine · 2026Article
- Lipid metabolism of hepatocyte-like cells supports intestinal tumor growth in Drosophila.Nature communications · 2026Article
379 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
20 authors at 8 institutions in 4 countries.
Haiping WangDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Fabien FrancoDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Yao-Chen TsuiDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Xin XieCenter for Genomics and Systems Biology, NYU Abu Dhabi, Abu Dhabi, United Arab Emirates.ORCID http://orcid.org/0000-0002-6784-4860
Marcel P TrefnyDepartment of Biomedicine, Laboratory of Cancer Immunology, University Hospital and University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0001-6755-7899
Roberta ZappasodiLudwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Syed Raza MohmoodCenter for Genomics and Systems Biology, NYU Abu Dhabi, Abu Dhabi, United Arab Emirates.
Juan Fernández-GarcíaLaboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.
Chin-Hsien TsaiDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Isabell SchulzeLudwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Florence PicardDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Etienne MeylanSwiss Institute for Experimental Cancer Research, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-0899-2230
Roy SilversteinDepartment of Medicine, Medical College of Wisconsin, Wauwatosa, WI, USA.
Ira GoldbergDepartment of Medicine, NYU Langone Health, New York, NY, USA.
Sarah-Maria FendtLaboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.ORCID http://orcid.org/0000-0001-6018-9296
Jedd D WolchokLudwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-6718-2222
Taha MerghoubLudwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-1518-5111
Camilla JandusDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-7405-5747
Alfred ZippeliusDepartment of Biomedicine, Laboratory of Cancer Immunology, University Hospital and University of Basel, Basel, Switzerland.
Ping-Chih HoDepartment of Oncology, University of Lausanne, Lausanne, Switzerland. ping-chih.ho@unil.ch.ORCID http://orcid.org/0000-0003-3078-3774
Ludwig Cancer Research · CHMemorial Sloan Kettering Cancer Center · USNew York University Abu Dhabi · AEUniversity of Basel · CHVIB-KU Leuven Center for Cancer Biology · BEÉcole Polytechnique Fédérale de Lausanne · CHMedical College of Wisconsin · USNYU Langone Health · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MVascular signaling via scavenger receptorsP01HL046403 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI HAJJAR, KATHERINE AMBERSON · 1991 to 2011
$26.7MREGULATION OF MONOCYTE 15-LIPOXYGENASE EXPRESSIONP01HL087018 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI MCINTYRE, THOMAS M · 2007 to 2011
$11.4MPathways of Tissue Lipid UptakeR01HL045095 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ABUMRAD, NADA A., GOLDBERG, IRA J · 1991 to 2024
$6.9MMechanisms of Fatty Acid Uptake By Cardiac MuscleR01HL073029 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GOLDBERG, IRA J · 2003 to 2021
$6.8MIMMUNIZATION AGAINST MELANOMA DIFFERENTIATION ANTIGENSR01CA056821 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI WOLCHOK, JEDD D. · 1992 to 2020
$5.7MEXTRACELLULAR REGULATION OF LIPOPROTEIN LIPASE ACTIVITYR37HL045095 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOLDBERG, IRA J · 2000 to 2009
$4.6MERK5 and CD36 link oxidative stress to platelet dysfunction and ischemic injuryR01HL142152 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI MORRELL, CRAIG N, SILVERSTEIN, ROY L · 2019 to 2022
$2.5MRole of MMPs in AngII induced abdominal aortic aneurysmsR01HL070239 · NHLBI · UNIVERSITY OF KENTUCKY · PI DAUGHERTY, ALAN · 2002 to 2005
$1.8MNCI NIH HHS P30 CA008748NCI NIH HHS R01 CA056821NHLBI NIH HHS P01 HL046403NHLBI NIH HHS P01 HL087018NHLBI NIH HHS R01 HL045095NHLBI NIH HHS R01 HL070239NHLBI NIH HHS R01 HL073029NHLBI NIH HHS R01 HL142152NHLBI NIH HHS R37 HL045095Swiss National Science Foundation 163204
Abstract
Depleting regulatory T cells (T
Indexed as
AnimalsApoptosisCD36 AntigensCell Line, TumorFemaleHomeostasisHumansImmunotherapyLipid MetabolismLymphocytes, Tumor-InfiltratingMaleMiceMice, Inbred C57BLMice, KnockoutNeoplasmsPPAR-betaCD36 AntigensCD36 protein, humanCd36 protein, mousePPAR-beta
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