ArticleNature communications2020
A disinhibitory nigra-parafascicular pathway amplifies seizure in temporal lobe epilepsy.
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In one paragraph
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
What it found
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Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.
- Bibliometric and visualized analysis of current advances and future directions in epilepsy: from molecular basis to therapy.Frontiers in neurology · 2025Pooled it
- The basal ganglia and the epilepsies.Epilepsia open · 2026Review
- Article
- Integrating multisequence radiomics and clinical features to predict seizure recurrence after gross total resection of pediatric low-grade epilepsy-associated brain tumors.Neuroradiology · 2026Article
- Acquired pharmacoresistance in temporal lobe epilepsy is driven by NaActa pharmaceutica Sinica. B · 2026Article
- TREM2-mediated microglial phagocytosis of inhibitory synapses contributes to prolonged FS-induced epileptogenesis.Cell death discovery · 2026Article
- Nanophotonic neural probes for in vivo photostimulation, electrophysiology, and microfluidic delivery.Microsystems & nanoengineering · 2026Article
- Model-Dependent Attenuation of Seizures by Cinnabar.Neuroscience bulletin · 2026Article
- Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ventral subicular pyramidal neurons contribute to epileptogenesis via anterior thalamic circuit.Communications biology · 2025Article
- Rethinking parvalbumin: From passive marker to active modulator of hippocampal circuits.IBRO neuroscience reports · 2025Article
- Cell-type-specific networks during hippocampal seizures at the micro- and macroscale.Brain : a journal of neurology · 2025Article
- Article
- Inhibiting astrocyte calcium dynamics terminates status epilepticus via wireless septal stimulation.Scientific reports · 2025Article
- Prediction of Pharmacoresistance in Drug-Naïve Temporal Lobe Epilepsy Using Ictal EEGs Based on Convolutional Neural Network.Neuroscience bulletin · 2025Article
- Attenuated PINK1 autophosphorylation play neuroprotective and anti-seizure roles in neonatal hypoxia.Scientific reports · 2025Article
- Circuit Reorganization of Subicular Cell-Type-Specific Interneurons in Temporal Lobe Epilepsy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Suppression of epileptic seizures by transcranial activation of KNature communications · 2025Article
- Brain Fog: a Narrative Review of the Most Common Mysterious Cognitive Disorder in COVID-19.Molecular neurobiology · 2024Review
- Enriched Environment Reduces Seizure Susceptibility via Entorhinal Cortex Circuit Augmented Adult Neurogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors at 3 institutions in 1 country.
Bin Chen *Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0001-7653-0399
Cenglin Xu *Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-4337-3777
Yi Wang *Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. wang-yi@zju.edu.cn.ORCID http://orcid.org/0000-0002-1350-2961
Wenkai Lin *Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0003-2568-9257
Ying WangKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0003-4616-031X
Liying ChenKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Heming ChengKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-9253-4987
Lingyu XuKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Tingting HuKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0001-8017-2619
Junli ZhaoKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0003-4751-3172
Ping DongKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-6640-6607
Yi GuoEpilepsy Center, Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-9128-4779
Shihong ZhangKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0003-3519-977X
Shuang WangEpilepsy Center, Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yudong ZhouKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-6364-3869
Weiwei HuKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-7768-6907
Shuming DuanKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Zhong ChenKey Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Pharmacology, School of Basic Medical Sciences, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. chenzhong@zju.edu.cn.ORCID http://orcid.org/0000-0003-4755-9357
Zhejiang University · CNZhejiang Chinese Medical University · CNSecond Affiliated Hospital of Zhejiang University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
The precise circuit of the substantia nigra pars reticulata (SNr) involved in temporal lobe epilepsy (TLE) is still unclear. Here we found that optogenetic or chemogenetic activation of SNr parvalbumin
Indexed as
AnimalsDisease Models, AnimalElectrodes, ImplantedEpilepsy, Temporal LobeGABAergic NeuronsHumansIntralaminar Thalamic NucleiMaleMiceMice, TransgenicNeural PathwaysOptogeneticsPatch-Clamp TechniquesSeverity of Illness IndexStereotaxic TechniquesSubstantia Nigra
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.