SynthesisTranslational psychiatry2020
Do nonpharmacological interventions prevent cognitive decline? a systematic review and meta-analysis.
Synthesis in Translational psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Digital health interventions for older adults with subjective cognitive decline or mild cognitive impairment: a systematic review and meta-analysis of randomized controlled trials.BMC geriatrics · 2026Pooled it
- Comparative efficacy and safety of multiple acupuncture therapies for post stroke cognitive impairment: a network meta-analysis of randomized controlled trials.Frontiers in neurology · 2023Pooled it
- Comparative efficacy of acupuncture-related techniques for mild cognitive impairment: A Bayesian network analysis.Frontiers in neurology · 2022Pooled it
- Effectiveness and Safety of Acupuncture for Vascular Cognitive Impairment: A Systematic Review and Meta-Analysis.Frontiers in aging neuroscience · 2021Pooled it
- Trial
- Effects of Traditional and Technology-Based Exercise Interventions on Cognitive Function in Older Adults: A Systematic Review and Meta-Analysis.Journal of Intelligence · 2026Review
- Effectiveness of Multisensory Stimulation on Cognitive Function in Older Adults With Mild Cognitive Impairment: Protocol for a Systematic Review.JMIR research protocols · 2026Article
- Peripheral Sensory Stimulation for Long-Term Improvement in Mild Cognitive Decline: A Prospective Interventional Study.Brain sciences · 2026Article
- Association between malnutrition and cognitive decline in Chinese older adults: the mediating role of physical frailty.Frontiers in public health · 2026Article
- The association between atherogenic index of plasma and cognitive impairment among older adults in Southern Iran: findings from the Bushehr elderly health program.BMC geriatrics · 2025Article
- Mobile Gaming for Cognitive Health in Older Adults: A Scoping Review of App Store Applications.Healthcare (Basel, Switzerland) · 2025Review
- Very high high-density lipoprotein cholesterol may be associated with higher risk of cognitive impairment in older adults.Nutrition journal · 2024Article
- Association between Depressive Mood, Antidepressant Therapy and Neuropsychological Performances: Results from a Cross-Sectional Study on Elderly Patients.Brain sciences · 2024Article
- Considerations on How to Prevent Parkinson's Disease Through Exercise.Journal of Parkinson's disease · 2024Review
- How do you target cognitive training? Bridging the gap between standard and technological rehabilitation of cognitive domains.Frontiers in psychology · 2024Article
- Exploring the neural and behavioral correlates of cognitive telerehabilitation in mild cognitive impairment with three distinct approaches.Frontiers in aging neuroscience · 2024Article
- Long-lasting improvements in episodic memory among subjects with mild cognitive impairment who received transcranial direct current stimulation combined with cognitive treatment and telerehabilitation: a multicentre, randomized, active-controlled study.Frontiers in aging neuroscience · 2024Article
- Effectiveness of an Online Dementia Prevention Program on Cognitive Function and Depression in Community-Dwelling Older Adults during the COVID-19 Pandemic in Korea.Healthcare (Basel, Switzerland) · 2023Article
- Mediterranean Diet, Ketogenic Diet or MIND Diet for Aging Populations with Cognitive Decline: A Systematic Review.Life (Basel, Switzerland) · 2023Review
- The aging mind: A complex challenge for research and practice.Aging brain · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
At present, prevention is particularly important when there is no effective treatment for cognitive decline. Since the adverse events of pharmacological interventions counterbalance the benefits, nonpharmacological approaches seem desirable to prevent cognitive decline. To our knowledge, no meta-analyses have been published on nonpharmacological interventions preventing cognitive decline. To investigate whether nonpharmacological interventions play a role in preventing cognitive decline among older people, we searched related trials up to March 31, 2019, in MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials and the Cochrane library databases. Randomized controlled trials (RCTs) were included if they enrolled participants older than 60 years of age who had a risk of cognitive decline, and the interventions were nonpharmacological. Two reviewers independently extracted data and assessed study quality. The Grading of Recommendations Assessment Development and Evaluation (GRADE) approach was used to rate the quality of evidence. Heterogeneity was quantified with I
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.