Evidence map›Paper›PMID 32066689›Full record

ArticleTranslational psychiatry2020

Delayed sleep timing and circadian rhythms in pregnancy and transdiagnostic symptoms associated with postpartum depression.

Jessica L Obeysekare, Zachary L Cohen, Meredith E Coles, Teri B Pearlstein, Carmen Monzon, E Ellen Flynn, Katherine M Sharkey

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jessica L ObeysekareDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, 700 Butler Drive, Providence, RI, 02906, USA.
Zachary L CohenDepartment of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, Chapel Hill, NC, 27514, USA.
Meredith E ColesDepartment of Psychology, Binghamton University (SUNY), Binghamton, NY, 13902, USA.
Teri B PearlsteinDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, 700 Butler Drive, Providence, RI, 02906, USA.
Carmen MonzonDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, 700 Butler Drive, Providence, RI, 02906, USA.
E Ellen FlynnDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, 700 Butler Drive, Providence, RI, 02906, USA.
Katherine M SharkeyDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, 700 Butler Drive, Providence, RI, 02906, USA. katherine_sharkey@brown.edu.ORCID http://orcid.org/0000-0003-1743-0704
Brown University · USBinghamton University · USProvidence College · USUniversity of North Carolina at Chapel Hill · US

Funding

Postpartum Depression: Role of Sleep & Genetic Risk in Postpartum Mood DisordersK23MH086689 · NIMH · RHODE ISLAND HOSPITAL · PI SHARKEY, KATHERINE M · 2011 to 2015
$831k
Warren Alpert Medical School Basic Translational ResearchT35HL094308 · NHLBI · BROWN UNIVERSITY · PI Thomas Benedict Bartnikas, Brittany Star Hampton · 2009 to 2026
$808k
NHLBI NIH HHS T35 HL094308NIMH NIH HHS K23 MH086689U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) T35HL094308
6 · The paper itself

Abstract

Later sleep timing, circadian preference, and circadian rhythm timing predict worse outcomes across multiple domains, including mood disorders, substance use, impulse control, and cognitive function. Disturbed sleep is common among pregnant and postpartum women. We examined whether sleep timing during third trimester of pregnancy predicted postpartum symptoms of mania, depression, and obsessive-compulsive disorder (OCD). Fifty-one women with a previous, but not active, episode of unipolar or bipolar depression had symptoms evaluated and sleep recorded with wrist actigraphy at 33 weeks of gestation and 2, 6, and 16 weeks postpartum. Circadian phase was measured in a subset of women using salivary dim light melatonin onset (DLMO). We divided the sample into "early sleep" and "late sleep" groups using average sleep onset time at 33 weeks of gestation, defined by the median-split time of 11:27 p.m. The "late sleep" group reported significantly more manic and depressive symptoms at postpartum week 2. Longer phase angle between DLMO and sleep onset at 33 weeks was associated with more manic symptoms at postpartum week 2 and more obsessive-compulsive symptoms at week 6. Delayed sleep timing in this sample of at-risk women was associated with more symptoms of mania, depression, and OCD in the postpartum period. Sleep timing may be a modifiable risk factor for postpartum depression.

Indexed as

Depression, PostpartumMelatoninActigraphyCircadian RhythmFemaleHumansPregnancySleepMelatonin

Identifiers

PMID32066689
PMCPMC7026062
OpenAlexW3001990356

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.