Evidence map›Paper›PMID 32066684›Full record

ReviewTranslational psychiatry2020

Delaying memory decline: different options and emerging solutions.

Felicitas Schneider, Alan Horowitz, Klaus-Peter Lesch, Thomas Dandekar

Open access · goldAbstract readReview
In one paragraph

Review in Translational psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. A structured pathway for developing your complex abdominal hernia service: our York pathway.Hernia : the journal of hernias and abdominal wall surgery · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Felicitas SchneiderDepartment of Bioinformatics, Biocenter, University of Würzburg, 97074, Würzburg, Germany.
Alan HorowitzDepartment of Bioinformatics, Biocenter, University of Würzburg, 97074, Würzburg, Germany.
Klaus-Peter LeschDivision of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, University of Würzburg, Würzburg, Germany.
Thomas DandekarDepartment of Bioinformatics, Biocenter, University of Würzburg, 97074, Würzburg, Germany. dandekar@biozentrum.uni-wuerzburg.de.ORCID http://orcid.org/0000-0003-1886-7625
University of Würzburg · DEEuropean Molecular Biology Organization · DESechenov University · RU

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 3 74031971 - TRR 240/Z2
6 · The paper itself

Abstract

Memory decline can be a devastating disease and increases in aging Western populations. Memory enhancement technologies hold promise for this and other conditions. Approaches include stem cell transplantation, which improved memory in several animal studies as well as vaccination against Alzheimer´s disease (AD) by β-amyloid antibodies. For a positive clinical effect, the vaccine should probably be administered over a long period of time and before amyloid pathologies manifest in the brain. Different drugs, such as erythropoietin or antiplatelet therapy, improve memory in neuropsychiatric diseases or AD or at least in animal studies. Omega-3 polyunsaturated fatty acid-rich diets improve memory through the gut-brain axis by altering the gut flora through probiotics. Sports, dancing, and memory techniques (e.g., Method of Loci) utilize behavioral approaches for memory enhancement, and were effective in several studies. Augmented reality (AR) is an auspicious way for enhancing memory in real time. Future approaches may include memory prosthesis for head-injured patients and light therapy for restoring memory in AD. Memory enhancement in humans in health and disease holds big promises for the future. Memory training helps only in mild or no impairment. Clinical application requires further investigation.

Indexed as

Alzheimer DiseaseMemoryAmyloid beta-PeptidesAnimalsBrainHumansMemory DisordersAmyloid beta-Peptides

Identifiers

PMID32066684
PMCPMC7026464
OpenAlexW3003074896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.