ArticleRegional anesthesia and pain medicine2020
Thoracoscopic lung biopsy under regional anesthesia for interstitial lung disease.
Article in Regional anesthesia and pain medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- The future of lung cancer surgery lies between innovations: synergy across the perioperative ERATS pathway.Frontiers in oncology · 2026Review
- Advancing thoracic surgery: the clinical, economic, and environmental promise of nonintubated video-assisted thoracoscopic surgery (NIVATS).British journal of anaesthesia · 2025Article
- Spontaneous Ventilation Thoracoscopic Lung Biopsy in Undetermined Interstitial Lung Disease: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Thoracic surgery in the non-intubated spontaneously breathing patient.Respiratory research · 2022Review
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundInterstitial lung disease (ILD) management guidelines support lung biopsy-guided therapy. However, the high mortality associated with thoracoscopic lung biopsy using general anesthesia (GA) in patients with ILD has deterred physicians from offering this procedure and adopt a diagnostic approach based on high-resolution CT. Here we report that thoracoscopy under regional anesthesia could be a safer alternative for lung biopsy and effectively guide ILD treatment.
methodsThis was a single-center retrospective review of prospectively maintained database and consisted of patients who underwent thoracoscopic lung biopsy between March 2016 and March 2018. Patients were divided into two groups: (A) GA, and (B) regional anesthesia using monitored anesthesia care (MAC) and thoracic epidural anesthesia (TEA).
resultsDuring the study period, 44 patients underwent thoracoscopic lung biopsy. Of these, 15 underwent MAC/TEA. There were no significant differences between the two groups with regard to pulmonary function test and clinicodemographic profile. However, operative time and hospital stay were shorter in MAC/TEA group (32.5±18.5 min vs 50.8±18.4; p=0.004, 1.0±1.3 days vs 10.0±34.7 days; p<0.001, respectively). Eight patients in the GA group, but none in the MAC/TEA group, experienced worsening of ILD after lung biopsy (p=0.03). Additionally, one patient in the GA group died due to acute ILD worsening. No cases of MAC/TEA group had to be converted to GA. In all cases a pathological diagnosis could be made.
conclusionsThoracoscopy using regional anesthesia might be a safer alternative to lung biopsy in patients with ILD.
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Registered trials
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