Evidence map›Paper›PMID 32066522›Full record

ArticleeLife2020

Wenn-Chyau Lee, Bruce Russell, Radoslaw Mikolaj Sobota, Khairunnisa Ghaffar, Shanshan W Howland, Zi Xin Wong, Alexander G Maier, Dominique Dorin-Semblat, Subhra Biswas, Benoit Gamain and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Ethanolic Leaf Extract ofTropical medicine and infectious disease · 2026
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  3. Review
  4. Review
  5. Effect of periostin (OSF-2) on phagocytosis ofFrontiers in microbiology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Rosette formation byFrontiers in cellular and infection microbiology · 2023
    Article
  11. Review
  12. Article
  13. Cytoadherence Properties ofFrontiers in microbiology · 2021
    Article
  14. Lessons Learned for Pathogenesis, Immunology, and Disease of Erythrocytic Parasites:Frontiers in cellular and infection microbiology · 2021
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 8 countries.

Wenn-Chyau LeeSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-7324-5792
Bruce RussellDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Radoslaw Mikolaj SobotaSystems Structural Biology Group, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Khairunnisa GhaffarSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Shanshan W HowlandSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Zi Xin WongSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Alexander G MaierBiomedical Sciences and Biochemistry, Research School of Biology, Australian National University, Canberra, Australia.
Dominique Dorin-SemblatUniversité de Paris, Biologie Intégrée du Globule Rouge, UMR_S1134, BIGR, INSERM, Paris, France.
Subhra BiswasSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Benoit GamainUniversité de Paris, Biologie Intégrée du Globule Rouge, UMR_S1134, BIGR, INSERM, Paris, France.
Yee-Ling LauDepartment of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Benoit MalleretSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Cindy ChuShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
François NostenShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.ORCID 0000-0002-7951-0745
Laurent ReniaSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0003-0349-1557
Agency for Science, Technology and Research · SGInserm · FRMahidol University · THAustralian National University · AUUniversity of Malaya · MYUniversity of Otago · NZ

Funding

Wellcome Trust
6 · The paper itself

Abstract

In malaria, rosetting is described as a phenomenon where an infected erythrocyte (IRBC) is attached to uninfected erythrocytes (URBC). In some studies, rosetting has been associated with malaria pathogenesis. Here, we have identified a new type of rosetting. Using a step-by-step approach, we identified IGFBP7, a protein secreted by monocytes in response to parasite stimulation, as a rosette-stimulator for

Indexed as

PhagocytosisCulture MediaErythrocytesHumansInsulin-Like Growth Factor Binding ProteinsLigandsNeutralization TestsPlasmodium falciparumPlasmodium vivaxTHP-1 CellsCulture Mediainsulin-like growth factor binding protein-related protein 1Insulin-Like Growth Factor Binding ProteinsLigandshost-parasite interactionIGFBP7immunologyinfectious diseaseinflammationmicrobiologyP. falciparumphagocytosisP. vivaxrosette

Identifiers

PMID32066522
PMCPMC7048393
OpenAlexW3007467225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.