Evidence map›Paper›PMID 32066397›Full record

ArticleBMC infectious diseases2020

The influence of race in older adults with infective endocarditis.

Ché Matthew Harris, Waseem Khaliq, Aiham Albaeni, Keith C Norris

Erratum issuedOpen access · goldAbstract readComparative Study
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ché Matthew HarrisDepartment of General Internal Medicine, Johns Hopkins School of Medicine, Division of Hospital Medicine Johns Hopkins Bayview Medical Center, 5200 Eastern Avenue, Baltimore, MD, 21224, USA. charri21@jhmi.edu.ORCID http://orcid.org/0000-0002-8010-9449
Waseem KhaliqDepartment of General Internal Medicine, Johns Hopkins School of Medicine, Division of Hospital Medicine Johns Hopkins Bayview Medical Center, 5200 Eastern Avenue, Baltimore, MD, 21224, USA.
Aiham AlbaeniDepartment of Medicine, Division of Cardiology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0570, USA.
Keith C NorrisDepartment of Internal Medicine, Division of Nephrology, David Geffen School of Medicine, University of California Los Angeles, California, Los Angeles, USA.
Johns Hopkins University · USThe University of Texas Medical Branch at Galveston · USUniversity of California, Los Angeles · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
The Center for Health Improvement of Minority ElderlyP30AG021684 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CATHERINE A SARKISIAN · 2002 to 2026
$19.7M
Obesity Health Disparities Research PRIDE Program (OHD PRIDE)R25HL126145 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI BEECH, BETTINA M., BRUCE, MARINO A · 2014 to 2025
$3.9M
NHLBI NIH HHS 1R25HL126145-01NHLBI NIH HHS R25 HL126145NIA NIH HHS P30 AG021684NIH HHS P30AG021684NIH HHS UL1TR000124
6 · The paper itself

Abstract

backgroundAge is a risk factor for infective endocarditis, and almost half of diagnosed patients are age ≥ 60 years. Large national studies have not evaluated inpatient mortality and surgical valvular interventions between older White and Black patients hospitalized with infective endocarditis.

methodsWe used the Nationwide Inpatient Sample database to identify older adults ≥60 years in North America with a principle diagnosis of infective endocarditis. Multivariate logistic regression was used to compare in-hospital mortality and valvular repairs/replacement between older Black and White patients.

resultsOf 10,390 adults, age ≥ 60 years hospitalized for infective endocarditis during 2013 and 2014, 7356 were White and 1089 Black. Blacks were younger (mean age: 70.5 ± 0.5 vs. 73.5 ± 0.2 years, p < 0.01), lived in more zip codes with a median annual income <$39,000/yr. (40.4% vs 18.8%, p < 0.01), and had higher co-morbidity burden (Charlson comorbidity score ≥ 3: 54.6% vs 40.7%, p < 0.01). After multivariate adjustment, Blacks had higher odds for in-hospital mortality (Odds Ratio (OR) = 2.0, [Confidence Interval (CI) 1.1-3.8]; p = 0.020), and lower odds for mitral valve repairs/replacements (OR = 0.53, CI: 0.29-0.99, p = 0.049).

conclusionsBlacks age ≥ 60 years hospitalized in North America with infective endocarditis are less likely to undergo mitral valvular repairs/replacement and had higher in-hospital mortality compared to White patients.

Indexed as

AgedBlack or African AmericanCardiac Valve AnnuloplastyDatabases, FactualEndocarditisFemaleHospital MortalityHumansLogistic ModelsMaleMiddle AgedNorth AmericaRace FactorsRisk FactorsWhite PeopleEndocarditisHospitalizationsLarge databaseMortalityRacial disparities

Identifiers

PMID32066397
PMCPMC7027119
OpenAlexW3006933154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.