Evidence map›Paper›PMID 32065970›Full record

ArticleJournal of psychosomatic research2020

Mental health concerns in patients with symptomatic peripheral artery disease: Insights from the PORTRAIT registry.

Merrill Thomas, Krishna K Patel, Kensey Gosch, Clementine Labrosciano, Carlos Mena-Hurtado, Robert Fitridge, John A Spertus, Kim G Smolderen

Abstract read
In one paragraph

Article in Journal of psychosomatic research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Anxiety and peripheral artery disease.Clinical science (London, England : 1979) · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Impact of physical activity on self-reported health parameters in peripheral artery disease in two periods of the COVID-19 pandemic.Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing · 2023
    Article
  10. Article
  11. Disease-Specific Quality of Life among Patients with Peripheral Artery Disease in Hungary.International journal of environmental research and public health · 2023
    Article
  12. Article
  13. Impact of the COVID-19 pandemic on health lifestyle in patients with peripheral artery disease: A cross-sectional study.Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Merrill ThomasUniversity of Missouri-Kansas City School of Medicine, 2411 Holmes Street, Kansas City, MO 64108, United States of America; Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, United States of America.
Krishna K PatelUniversity of Missouri-Kansas City School of Medicine, 2411 Holmes Street, Kansas City, MO 64108, United States of America; Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, United States of America.
Kensey GoschSaint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, United States of America.
Clementine LabroscianoDiscipline of Medicine, University of Adelaide, Adelaide, South Australia, Australia; Translational Vascular Function Research, Basil Hetzel Institute for Translational Research, Woodville, South Australia, Australia.
Carlos Mena-HurtadoYale New Haven Hospital, Yale University, New Haven, CT, United States of America.
Robert FitridgeDiscipline of Surgery, Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.
John A SpertusUniversity of Missouri-Kansas City School of Medicine, 2411 Holmes Street, Kansas City, MO 64108, United States of America; Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, United States of America.
Kim G SmolderenUniversity of Missouri-Kansas City School of Medicine, 2411 Holmes Street, Kansas City, MO 64108, United States of America; Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, United States of America; Yale New Haven Hospital, Yale University, New Haven, CT, United States of America. Electronic address: kim.smolderen@yale.edu.

Funding

CARDIOVASCULAR OUTCOMES RESEARCH TRAINING PROGRAMT32HL110837 · NHLBI · UNIVERSITY OF MISSOURI KANSAS CITY · PI JOHN A SPERTUS · 2012 to 2026
$5.0M
NHLBI NIH HHS T32 HL110837
6 · The paper itself

Abstract

objectivesTo document the prevalence and patient profiles of mental health concerns in patients with peripheral artery disease (PAD) seen in the vascular specialty setting.

methodsIn a cohort of 1275 patients presenting to 16 specialty clinics with new or worsening claudication, symptoms of depression, anxiety, and stress were quantified in 957 patients. The Patient Health Questionnaire-8 (PHQ-8), Generalized Anxiety Disorder scale-2 (GAD-2), and Perceived Stress Scale-4 (PSS-4) were assessed for mental health concerns at the initial PAD work-up and repeated 12 months later. PHQ-8 ≥ 10, GAD-2 ≥ 3 and PSS-4 ≥ 6 were considered significant for depression, anxiety and stress respectively. Patient characteristics were compared in groups divided by presence of 0, 1, 2 or all 3 mental health concerns.

resultsOn the initial office visit, 336/957 (35%) of patients had high levels of at least one of the three mental health concerns. At both baseline and 12 months, high levels of perceived stress were most often reported (28.7% and 17.5% respectively), followed by symptoms of depression (14.1% and 8.9%) and then anxiety (8.3% and 5.7%). Patients with mental health concerns were more often female, younger, had more financial strain, less social support, and worse perceived health status.

conclusionsMental health concerns, particularly stress, are highly prevalent in patients with PAD, especially upon first presenting with new or worsening symptoms. The role of stress and how it may impede successful PAD management and impact subsequent outcomes warrants further investigation.

Indexed as

AnxietyDepressionPerceived stressVascular disease

Identifiers

PMID32065970
PMCPMC7417281

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.