Evidence map›Paper›PMID 32065704›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

How do highly sensitized patients get kidney transplants in the United States? Trends over the last decade.

Kyle R Jackson, Jennifer D Motter, Amber Kernodle, Niraj Desai, Alvin G Thomas, Allan B Massie, Jacqueline M Garonzik-Wang, Dorry L Segev

Abstract readMulticenter Study
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Five Years Follow-up of Imlifidase Desensitized Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Trial
  2. Outcomes at 3 years posttransplant in imlifidase-desensitized kidney transplant patients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Glycolysis Changes in Alloreactive Memory B Cells in Highly Sensitized Kidney Transplant Recipients Undergoing Desensitization Therapy.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  12. Article
  13. Early Effect of the Circular Model of Kidney Allocation in the United States.Journal of the American Society of Nephrology : JASN · 2023
    Article
  14. Review
  15. Dynamic Behaviour of Donor Specific Antibodies in the Early Period Following HLA Incompatible Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Article
  16. Article
  17. Article
  18. Kidney transplantation in highly sensitized recipients.Kidney research and clinical practice · 2021
    Article
  19. The first increase in live kidney donation in the United States in 15 years.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kyle R JacksonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-8135-5377
Jennifer D MotterDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Amber KernodleDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-6459-5280
Niraj DesaiDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Alvin G ThomasDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Allan B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jacqueline M Garonzik-WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-3205-1024

Funding

Cardiovascular Epidemiology Training GrantT32HL007055 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wayne D. Rosamond · 1986 to 2026
$10.0M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Determinants of chronic kidney disease in African-American live kidney donorsK01DK101677 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MASSIE, ALLAN B · 2015 to 2019
$789k
Aggressive Center Report Cards to Safely Increase Transplantation of Suboptimal KidneysK23DK115908 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GARONZIK WANG, JACQUELINE M · 2018 to 2021
$516k
The effect of socioeconomic status and environment characteristics on disparate postdonation health outcomes between Black and White living kidney donorsF32DK117563 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI KERNODLE, AMBER · 2018 to 2020
$240k
Differential Survival Benefit of Incompatible Living Donor Kidney Transplantation: Modeling Outcomes for Different Patient PhenotypesF32DK113719 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI JACKSON, KYLE R · 2017 to 2019
$238k
NHLBI NIH HHS T32 HL007055NIAID NIH HHS K24 AI144954NIDDK NIH HHS F32 DK113719NIDDK NIH HHS F32DK113719NIDDK NIH HHS F32 DK117563NIDDK NIH HHS F32DK117563NIDDK NIH HHS K01 DK101677NIDDK NIH HHS K01DK101677NIDDK NIH HHS K23 DK115908NIDDK NIH HHS K23DK115908NIDDK NIH HHS K24 DK101828NIDDK NIH HHS K24DK101828
6 · The paper itself

Abstract

Prioritization of highly sensitized (HS) candidates under the kidney allocation system (KAS) and growth of large, multicenter kidney-paired donation (KPD) clearinghouses have broadened the transplant modalities available to HS candidates. To quantify temporal trends in utilization of these modalities, we used SRTR data from 2009 to 2017 to study 39 907 adult HS (cPRA ≥ 80%) waitlisted candidates and 19 003 recipients. We used competing risks regression to quantify temporal trends in likelihood of DDKT, KPD, and non-KPD LDKT for HS candidates (Era 1: January 1, 2009-December 31, 2011; Era 2: January 1, 2012-December 3, 2014; Era 3: December 4, 2014-December 31, 2017). Although the likelihood of DDKT and KPD increased over time for all HS candidates (adjusted subhazard ratio [aSHR] Era 3 vs 1 for DDKT:

Indexed as

Kidney TransplantationTissue and Organ ProcurementTransplantsAdultDonor SelectionHumansLiving DonorsTissue and Organ HarvestingUnited Statesclinical research/practicedonors and donation: deceaseddonors and donation: paired exchangehealth services and outcomes researchkidney transplantation/nephrologypanel reactive antibody (PRA)registry/registry analysis

Identifiers

PMID32065704
PMCPMC8717833

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.