Evidence map›Paper›PMID 32065480›Full record

ArticleDepression and anxiety2020

Stability of chronotype over a 7-year follow-up period and its association with severity of depressive and anxiety symptoms.

Stella J M Druiven, Johanna H M Hovenkamp-Hermelink, Stefan E Knapen, Jeanine Kamphuis, Benno C M Haarman, Brenda W J H Penninx, Niki Antypa, Ybe Meesters, Robert A Schoevers, Harriëtte Riese

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Article in Depression and anxiety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Role of chronotype in depression.World journal of psychiatry · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stella J M DruivenDepartment of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-3270-4809
Johanna H M Hovenkamp-HermelinkDepartment of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-8661-3382
Stefan E KnapenDepartment of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-2038-9474
Jeanine KamphuisDepartment of Psychiatry, Research School of Behavioral and Cognitive Neurosciences (BCN), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Benno C M HaarmanDepartment of Psychiatry, Research School of Behavioral and Cognitive Neurosciences (BCN), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-9006-8863
Brenda W J H PenninxDepartment of Psychiatry, EMGO+ Institute, VU University Medical Center, Amsterdam, The Netherlands.ORCID 0000-0001-7779-9672
Niki AntypaDepartment of Clinical Psychology, Institute of Psychology, Leiden University, Leiden, The Netherlands.ORCID 0000-0001-9343-8842
Ybe MeestersDepartment of Psychiatry, Research School of Behavioral and Cognitive Neurosciences (BCN), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-1464-7799
Robert A SchoeversDepartment of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-0760-9866
Harriëtte RieseDepartment of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-3661-3151

Funding

ZonMw 10-000-1002
6 · The paper itself

Abstract

backgroundChronotype is an individual's preferred timing of sleep and activity, and is often referred to as a later chronotype (or evening-type) or an earlier chronotype (or morning-type). Having an evening chronotype is associated with more severe depressive and anxiety symptoms. Based on these findings it is has been suggested that chronotype is a stable construct associated with vulnerability to develop depressive or anxiety disorders. To examine this, we test the stability of chronotype over 7 years, and its longitudinal association with the change in severity of depressive and anxiety symptoms.

methodsData of 1,417 participants with a depressive and/or anxiety disorder diagnosis and healthy controls assessed at the 2 and 9-year follow-up waves of the Netherlands Study of depression and anxiety were used. Chronotype was assessed with the Munich chronotype questionnaire. Severity of depressive and anxiety symptoms were assessed with the inventory of depressive symptomatology and Beck anxiety inventory.

resultsChronotype was found to be moderately stable (r = 0.53) and on average advanced (i.e., became earlier) with 10.8 min over 7 years (p < .001). Controlling for possible confounders, a decrease in severity of depressive symptoms was associated with an advance in chronotype (B = 0.008, p = .003). A change in severity of anxiety symptoms was not associated with a change in chronotype.

conclusionChronotype was found to be a stable, trait-like construct with only a minor level advance over a period of 7 years. The change in chronotype was associated with a change in severity of depressive, but not anxiety, symptoms.

Indexed as

Sleep Initiation and Maintenance DisordersAdultAgedAnxietyCase-Control StudiesCircadian RhythmDepressionFemaleFollow-Up StudiesHumansMaleMiddle AgedNetherlandsSeverity of Illness IndexSleepSleep Wake Disordersanxiety symptomschronotypedepressive symptomstest-retest

Identifiers

PMID32065480
PMCPMC7318352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.