Evidence map›Paper›PMID 32065258›Full record

Trial reportEuropean journal of applied physiology2020

The acute effects of interrupting prolonged sitting with stair climbing on vascular and metabolic function after a high-fat meal.

Min Jeong Cho, Kanokwan Bunsawat, Hyun Jeong Kim, Eun Sun Yoon, Sae Young Jae

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Min Jeong ChoExercise and Cardiovascular Physiology Laboratory, Department of Sport Science, University of Seoul, Seoul, South Korea.
Kanokwan BunsawatDepartment of Internal Medicine, Division of Geriatrics, University of Utah, Salt Lake City, UT, USA.
Hyun Jeong KimExercise and Cardiovascular Physiology Laboratory, Department of Sport Science, University of Seoul, Seoul, South Korea.
Eun Sun YoonExercise and Cardiovascular Physiology Laboratory, Department of Sport Science, University of Seoul, Seoul, South Korea.
Sae Young JaeExercise and Cardiovascular Physiology Laboratory, Department of Sport Science, University of Seoul, Seoul, South Korea. syjae@uos.ac.kr.ORCID http://orcid.org/0000-0003-0358-7866
University of Seoul · KRUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFrequent consumption of high-fat meals and prolonged sedentary time are prevalent lifestyles that have been associated with an increased risk of vascular and metabolic complications. This study evaluated the acute effects of interrupting prolonged sitting with stair climbing on vascular and metabolic function after a high-fat meal.

methodsIn a randomized, cross-over trial, 12 healthy adults (age:  23.5 ± 2.9 years) consumed a high-fat meal, followed by either 1) a 4-h uninterrupted sitting (sitting trial) or 2) a 4-h sitting interrupted with a 5-min stair climbing (average intensity: 66% of heart rate reserve) every hour (interrupted trial). Plasma triglyceride and glucose concentrations, as well as popliteal artery blood flow and shear rate were assessed at baseline and every hour after a high-fat meal, whereas brachial artery flow-mediated dilation was assessed at baseline and again at the end of each trial.

resultsPlasma triglyceride and glucose concentrations increased after a high-fat meal and returned to baseline at the end of both trials. Following a high-fat meal, brachial artery flow-mediated dilation decreased in the sitting trial, but not in the interrupted trial (sitting trial: 9.65 ± 2.63% to 7.84 ± 2.36%; interrupted trial: 9.41 ± 2.61% to 10.34 ± 3.30%, p = 0.009 for interaction). Compared with the sitting trial, the interrupted trial improved popliteal blood flow and shear rate (p = 0.004 and p = 0.008 for interaction, respectively).

conclusionsThese findings suggest that interrupting prolonged sitting with stair climbing may be an effective lifestyle strategy to prevent against vascular dysfunction that might occur as a result of prolonged sitting after consuming a high-fat meal in young healthy adults.

Indexed as

Diet, High-FatSedentary BehaviorAdultCross-Over StudiesEndothelium, VascularFemaleHealthy VolunteersHumansHyperglycemiaHyperlipidemiasMalePostprandial PeriodStair ClimbingYoung AdultHigh-fat mealInterrupting prolonged sittingStair climbingVascular function

Identifiers

PMID32065258
OpenAlexW3005909188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.