Evidence map›Paper›PMID 32065245›Full record

ArticleSkeletal radiology2020

Is the immediate effect of marathon running on novice runners' knee joints sustained within 6 months after the run? A follow-up 3.0 T MRI study.

Laura Maria Horga, Johann Henckel, Anastasia Fotiadou, Anna C Hirschmann, Anna Di Laura, Camilla Torlasco, Andrew D'Silva, Sanjay Sharma, James C Moon, Alister J Hart

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In one paragraph

Article in Skeletal radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Laura Maria HorgaInstitute of Orthopaedics and Musculoskeletal Science, University College London and the Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, London, HA7 4LP, UK. laura.horga.17@ucl.ac.uk.ORCID http://orcid.org/0000-0003-1244-2140
Johann HenckelInstitute of Orthopaedics and Musculoskeletal Science, University College London and the Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, London, HA7 4LP, UK.
Anastasia FotiadouInstitute of Orthopaedics and Musculoskeletal Science, University College London and the Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, London, HA7 4LP, UK.
Anna C HirschmannDepartment of Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
Anna Di LauraInstitute of Orthopaedics and Musculoskeletal Science, University College London and the Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, London, HA7 4LP, UK.
Camilla TorlascoInstitute of Cardiovascular Science and Barts Heart Centre, University College London, London, UK.
Andrew D'SilvaDepartment of Cardiovascular Sciences, St George's University of London, London, UK.
Sanjay SharmaDepartment of Cardiovascular Sciences, St George's University of London, London, UK.
James C MoonInstitute of Cardiovascular Science and Barts Heart Centre, University College London, London, UK.
Alister J HartInstitute of Orthopaedics and Musculoskeletal Science, University College London and the Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, London, HA7 4LP, UK.
Royal National Orthopaedic Hospital · GBBritish Heart Foundation · GBSt George's, University of London · GBUniversity Hospital of Basel · CH

Funding

British Heart Foundation FS/15/27/31465patient donations patient donations
6 · The paper itself

Abstract

objectiveTo evaluate changes in the knee joints of asymptomatic first-time marathon runners, using 3.0 T MRI, 6 months after finishing marathon training and run. MATERIALS AND

methodsSix months after their participation in a baseline study regarding their knee joints, 44 asymptomatic novice marathoners (17 males, 27 females, mean age 46 years old) agreed to participate in a repeat MRI investigation: 37 completed both a standardized 4-month-long training programme and the marathon (marathon runners); and 7 dropped out during training (pre-race dropouts). The participants already underwent bilateral 3.0 T MRIs: 6 months before and 2 weeks after their first marathon, the London Marathon 2017. This study was a follow-up assessment of their knee joints. Each knee structure was assessed using validated scoring/grading systems at all time points.

resultsTwo weeks after the marathon, 3 pre-marathon bone marrow lesions and 2 cartilage lesions showed decrease in radiological score on MRI, and the improvement was sustained at the 6-month follow-up. New improvements were observed on MRI at follow-up: 5 pre-existing bone marrow lesions and 3 cartilage lesions that remained unchanged immediately after the marathon reduced in their extent 6 months later. No further lesions appeared at follow-up, and the 2-week post-marathon lesions showed signs of reversibility: 10 of 18 bone marrow oedema-like signals and 3 of 21 cartilage lesions decreased on MRI.

conclusionThe knees of novice runners achieved sustained improvement, for at least 6 months post-marathon, in the condition of their bone marrow and articular cartilage.

Indexed as

Marathon RunningAthletic InjuriesBone MarrowCartilage, ArticularEdemaFemaleFollow-Up StudiesHumansKnee InjuriesKnee JointLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesBoneCartilageKneeMarathon runningMRI

Identifiers

PMID32065245
PMCPMC7300102
OpenAlexW3007298598

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.