Evidence map›Paper›PMID 32065076›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

Guidelines for the content and format of PET brain data in publications and archives: A consensus paper.

Gitte M Knudsen, Melanie Ganz, Stefan Appelhoff, Ronald Boellaard, Guy Bormans, Richard E Carson, Ciprian Catana, Doris Doudet, Antony D Gee, Douglas N Greve and 34 more

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Trial
  2. Building an open infrastructure for molecular neuroimaging: Standards and tools from the OpenNeuroPET initiative.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  3. [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. PET Quantification in Healthy Humans of Cyclooxygenase-2, a Potential Biomarker of Neuroinflammation.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  9. Article
  10. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  11. Article
  12. Reporting checklists in neuroimaging: promoting transparency, replicability, and reproducibility.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Quantitation of dynamic total-body PET imaging: recent developments and future perspectives.European journal of nuclear medicine and molecular imaging · 2023
    Review
  17. Article
  18. An automatic analysis framework for FDOPA PET neuroimaging.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Gitte M KnudsenNeurobiology Research Unit, Rigshospital and University of Copenhagen, Copenhagen, Denmark.
Melanie GanzNeurobiology Research Unit, Rigshospital and University of Copenhagen, Copenhagen, Denmark.
Stefan AppelhoffCenter for Adaptive Rationality, Max Planck Institute for Human Development, Berlin, Germany.
Ronald BoellaardDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Guy BormansLaboratory for Radiopharmaceutical Research, KU, Leuven, Belgium.
Richard E CarsonDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, USA.
Ciprian CatanaAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Department of Radiology, Boston, MA, USA.
Doris DoudetDepartment of Medicine/Neurology, Pacific Parkinson Research Center, Vancouver, Canada.
Antony D GeeClinical PET Centre, King's College London, London, UK.ORCID 0000-0001-8389-9012
Douglas N GreveAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Department of Radiology, Boston, MA, USA.
Roger N GunnInvicro and Division of Brain Sciences, Imperial College London, London, UK.
Christer HalldinCenter for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.
Peter HerscovitchDepartment of Positron Emission Tomography, National Institutes of Health, Bethesda, USA.
Henry HuangDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, USA.
Sune H KellerDepartment of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Adriaan A LammertsmaDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Rupert LanzenbergerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Jeih-San LiowMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, USA.
Talakad G LohithTranslational Biomarkers, Merck & Co., West Point, USA.
Mark LubberinkUppsala University, Department of Surgical Sciences/Radiology and Nuclear Medicine, Uppsala University Hospital, Department of Medical Physics, Sweden.
Chul H LyooDepartment of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
J John MannDepartment of Psychiatry, Molecular Imaging and Neuropathology Division, Columbia University, New York, USA.
Granville J MathesonCenter for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.
Thomas E NicholsOxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, UK.ORCID 0000-0002-4516-5103
Martin NørgaardNeurobiology Research Unit, Rigshospital and University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-2131-5688
Todd OgdenColumbia Mailman School of Public Health, Columbia University, New York, USA.
Ramin ParseyDepartment of Psychiatry, School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Victor W PikeMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, USA.
Julie PriceAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Department of Radiology, Boston, MA, USA.
Gaia RizzoInvicro and Division of Brain Sciences, Imperial College London, London, UK.
Pedro Rosa-NetoMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada.
Martin SchainColumbia Mailman School of Public Health, Columbia University, New York, USA.
Peter Jh ScottDepartment of Radiology, University of Michigan, Ann Arbor, USA.
Graham SearleInvicro and Division of Brain Sciences, Imperial College London, London, UK.
Mark SlifsteinDepartment of Psychiatry, School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Tetsuya SuharaInstitute for Quantum Life Science, National Institute for Quantum and Radiological Science and Technology, Chiba, Japan.
Peter S TalbotDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Adam ThomasNational Institute of Mental Health, Bethesda, USA.
Mattia VeroneseCentre for Neuroimaging Sciences, King's College London, London, UK.
Dean F WongDepartment of Radiology, Johns Hopkins Hospital, Baltimore, USA.
Maqsood YaqubDepartment of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Francesca ZanderigoDepartment of Psychiatry, Columbia University, New York, USA.
Sami ZoghbiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, USA.
Robert B InnisMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8M
Clinical Evaluation of PET RadiotracersZIAMH002852 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$48.6M
Translational Evaluation Of PET RadiotracersZIAMH002795 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$32.0M
Data Science and Sharing TeamZICMH002960 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI THOMAS, ADAM G · 2017 to 2025
$10.3M
Intramural NIH HHS ZIA MH002795Intramural NIH HHS ZIA MH002852NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

It is a growing concern that outcomes of neuroimaging studies often cannot be replicated. To counteract this, the magnetic resonance (MR) neuroimaging community has promoted acquisition standards and created data sharing platforms, based on a consensus on how to organize and share MR neuroimaging data. Here, we take a similar approach to positron emission tomography (PET) data. To facilitate comparison of findings across studies, we first recommend publication standards for tracer characteristics, image acquisition, image preprocessing, and outcome estimation for PET neuroimaging data. The co-authors of this paper, representing more than 25 PET centers worldwide, voted to classify information as mandatory, recommended, or optional. Second, we describe a framework to facilitate data archiving and data sharing within and across centers. Because of the high cost of PET neuroimaging studies, sample sizes tend to be small and relatively few sites worldwide have the required multidisciplinary expertise to properly conduct and analyze PET studies. Data sharing will make it easier to combine datasets from different centers to achieve larger sample sizes and stronger statistical power to test hypotheses. The combining of datasets from different centers may be enhanced by adoption of a common set of best practices in data acquisition and analysis.

Indexed as

Practice Guidelines as TopicBrainConsensusFluorodeoxyglucose F18HumansImage Processing, Computer-AssistedNeuroimagingPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsFluorodeoxyglucose F18RadiopharmaceuticalsConsensus guidelinesdata sharingdata structureopen sourcepositron emission tomography

Identifiers

PMID32065076
PMCPMC7370374

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.