Evidence map›Paper›PMID 32064887›Full record

ArticleAntioxidants & redox signaling2020

Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids.

Soraia K P F Costa, Marcelo N Muscara, Thibault Allain, Jorge Dallazen, Larissa Gonzaga, Andre G Buret, David J Vaughan, Christopher J Fowler, Gilberto de Nucci, John L Wallace

Open access · hybridAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Hydrogen Sulfide Signaling in Neurodegenerative Movement Disorders.Handbook of experimental pharmacology · 2026
    Review
  5. Sulfide regulation and catabolism in health and disease.Signal transduction and targeted therapy · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Design, synthesis andJournal of enzyme inhibition and medicinal chemistry · 2021
    Article
  12. Review
  13. Novel Hydrogen Sulfide (HInternational journal of molecular sciences · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Soraia K P F CostaDepartment of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil.
Marcelo N MuscaraDepartment of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil.
Thibault AllainDepartment of Biological Sciences, University of Calgary, Alberta, Canada.
Jorge DallazenDepartment of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil.
Larissa GonzagaDepartment of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil.
Andre G BuretDepartment of Biological Sciences, University of Calgary, Alberta, Canada.
David J VaughanAntibe Therapeutics, Inc., Toronto, Canada.
Christopher J FowlerDepartment of Pharmacology and Clinical Neuroscience, Umeå University, Umeå, Sweden.
Gilberto de NucciDepartment of Pharmacology, University of Campinas, Campinas, Brazil.
John L WallaceAntibe Therapeutics, Inc., Toronto, Canada.
Universidade de São Paulo · BRUniversity of Calgary · CADecImmune Therapeutics (United States) · USUmeå University · SEUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnalgesicsAnimalsAnti-Inflammatory Agents, Non-SteroidalCannabinoidsDisease Models, AnimalDose-Response Relationship, RadiationDrug SynergismFatty AcidsGastric MucosaGastrointestinal TractHydrogen SulfideKetoprofenMicePainAnalgesicsAnti-Inflammatory Agents, Non-SteroidalCannabinoidsFatty AcidsHydrogen SulfideKetoprofenanalgesiccannabinoidhydrogen sulfideinflammationketoprofenpainulcer

Identifiers

PMID32064887
PMCPMC7578177
OpenAlexW3007758533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.