Evidence map›Paper›PMID 32064567›Full record

ArticleProgress in orthodontics2020

Clinical, microbiological, and immunological evaluation of patients in corrective orthodontic treatment.

Mariana Umekita Shirozaki, Raquel Assed Bezerra da Silva, Fábio Lourenço Romano, Léa Assed Bezerra da Silva, Andiara De Rossi, Marília Pacífico Lucisano, Michel Reis Messora, Magda Feres, Arthur Belém Novaes Júnior

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Progress in orthodontics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mariana Umekita ShirozakiDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café S/N, Ribeirão Preto, SP, 14040-904, Brazil.
Raquel Assed Bezerra da SilvaDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café S/N, Ribeirão Preto, SP, 14040-904, Brazil.
Fábio Lourenço RomanoDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café S/N, Ribeirão Preto, SP, 14040-904, Brazil.
Léa Assed Bezerra da SilvaDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café S/N, Ribeirão Preto, SP, 14040-904, Brazil.
Andiara De RossiDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café S/N, Ribeirão Preto, SP, 14040-904, Brazil.
Marília Pacífico LucisanoDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café S/N, Ribeirão Preto, SP, 14040-904, Brazil. marilia.lucisano@forp.usp.br.ORCID http://orcid.org/0000-0002-6866-0561
Michel Reis MessoraDepartment of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirao Preto, University of São Paulo, Avenida do Café S/N, Ribeirão Preto, SP, 14040-904, Brazil.
Magda FeresDepartment of Periodontology, Guarulhos University, Guarulhos, SP, Brazil.
Arthur Belém Novaes JúniorDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café S/N, Ribeirão Preto, SP, 14040-904, Brazil.
Universidade de São Paulo · BRGuarulhos University · BRUniversidade de Ribeirão Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective was to analyze clinical, microbiological, and immunological periodontal parameters in patients in corrective orthodontic treatment. MATERIALS AND

methodsTwenty-eight patients were selected. Plaque index (PI), bleeding on probing (BOP), width of keratinized gingiva, levels of 40 bacterial species, and of 3 cytokines (IL-1β, MMP-8, and TNF-α) in gingival crevicular fluid (GCF) were evaluated at T0, before orthodontic treatment; T1, 6 months; and T2, 12 months post-treatment. Non-parametric, Friedman, Wilcoxon, ANOVA, and Spearman correlation coefficient tests were used for statistical analyses, with the significance level of 5%.

resultsNo significant difference was found for the width of keratinized gingiva, but PI presented a significant increase at T1 and T2 (p < 0.05) when compared with T0. The percentage of sites with BOP increased significantly from T0 to T1 (p < 0.05); however, at T2, the values decreased and did not differ anymore from T0 (p > 0.05). In the microbiological analysis, red complex pathogens were in significantly greater proportions in T2 compared with T0 (p < 0.05). There was no statistically significant difference in the cytokine levels between the periods but there was a positive correlation between BOP and IL-1β (r = 0.49 p = .01) and TNF-α (r = 0.39 and p = .05).

conclusionIn conclusion, corrective orthodontic treatment caused clinical periodontal alterations regarding biofilm accumulation and gingival bleeding, with alteration of periodontopathogens.

Indexed as

Gingival Crevicular FluidOrthodontics, CorrectiveDental Plaque IndexHumansPeriodontal IndexTumor Necrosis Factor-alphaTumor Necrosis Factor-alphaBiofilmGingivitisOrthodonticsPeriodontology

Identifiers

PMID32064567
PMCPMC7024686
OpenAlexW3010810695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.