ArticleJournal of experimental botany2020
Endogenous ABA alleviates rice ammonium toxicity by reducing ROS and free ammonium via regulation of the SAPK9-bZIP20 pathway.
Article in Journal of experimental botany, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 82 citations in OpenAlex.
- Leaf Ontogeny Shapes Divergent Physiological and Metabolic Responses to Contrasting Nitrogen Forms in Chinese Fir (International journal of molecular sciences · 2026Article
- The Research Progress on the Effects of Phytohormones on Nitrogen Use Efficiency in Rice.Plants (Basel, Switzerland) · 2025Review
- CRISPR/Cas9-Mediated Knockout ofInternational journal of molecular sciences · 2025Article
- Physiological, transcriptomic, and genomic analysis unravels the response of Tatary buckwheat root to high ammonium stress.Frontiers in plant science · 2025Article
- Ion toxicity in waterlogged soils: mechanisms of root response and adaptive strategies.Frontiers in plant science · 2025Review
- FERONIA regulates salt tolerance in Arabidopsis by controlling photorespiratory flux.The Plant cell · 2024Article
- An Overview of the Mechanisms through Which Plants Regulate ROS Homeostasis under Cadmium Stress.Antioxidants (Basel, Switzerland) · 2024Review
- An AP2/ERF transcription factor confers chilling tolerance in rice.Science advances · 2024Article
- Identification of Wheat Glutamate Synthetase Gene Family and Expression Analysis under Nitrogen Stress.Genes · 2024Article
- Article
- Exogenous Abscisic Acid Affects the Heat Tolerance of Rice Seedlings by Influencing the Accumulation of ROS.Antioxidants (Basel, Switzerland) · 2023Article
- Site-2 Protease Slr1821 Regulates Carbon/Nitrogen Homeostasis during Ammonium Stress Acclimation in CyanobacteriumInternational journal of molecular sciences · 2023Article
- The rice SnRK family: biological roles and cell signaling modules.Frontiers in plant science · 2023Review
- TheBiology · 2022Article
- Review
- Gene expression analysis of resistant and susceptible rice cultivars to sheath blight after inoculation with Rhizoctonia solani.BMC genomics · 2022Article
- Integrated physiological and weighted gene co-expression network analysis reveals the hub genes engaged in nitrate-regulated alleviation of ammonium toxicity at the seedling stage in wheat (Frontiers in plant science · 2022Article
- CBL-Interacting Protein Kinase OsCIPK18 Regulates the Response of Ammonium Toxicity in Rice Roots.Frontiers in plant science · 2022Article
- OsANN4 modulates ROS production and mediates CaBMC plant biology · 2021Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ammonium (NH4+) is one of the principal nitrogen (N) sources in soils, but is typically toxic already at intermediate concentrations. The phytohormone abscisic acid (ABA) plays a pivotal role in responses to environmental stresses. However, the role of ABA under high-NH4+ stress in rice (Oryza sativa L.) is only marginally understood. Here, we report that elevated NH4+ can significantly accelerate tissue ABA accumulation. Mutants with high (Osaba8ox) and low levels of ABA (Osphs3-1) exhibit elevated tolerance or sensitivity to high-NH4+ stress, respectively. Furthermore, ABA can decrease NH4+-induced oxidative damage and tissue NH4+ accumulation by enhancing antioxidant and glutamine synthetase (GS)/glutamate synthetasae (GOGAT) enzyme activities. Using RNA sequencing and quantitative real-time PCR approaches, we ascertain that two genes, OsSAPK9 and OsbZIP20, are induced both by high NH4+ and by ABA. Our data indicate that OsSAPK9 interacts with OsbZIP20, and can phosphorylate OsbZIP20 and activate its function. When OsSAPK9 or OsbZIP20 are knocked out in rice, ABA-mediated antioxidant and GS/GOGAT activity enhancement under high-NH4+ stress disappear, and the two mutants are more sensitive to high-NH4+ stress compared with their wild types. Taken together, our results suggest that ABA plays a positive role in regulating the OsSAPK9-OsbZIP20 pathway in rice to increase tolerance to high-NH4+ stress.
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