ArticleMaterialia2019
Development of Phantom Material that Resembles Compression Properties of Human Brain Tissue for Training Models.
Article in Materialia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Multi-Layer Brain-Mimicking Phantom for Replicating Dura and Pia Membrane Dimpling and Rupture Properties During Neural Interface Implantation.bioRxiv : the preprint server for biology · 2026Article
- Gelatin-Based Head Phantoms: A Practical Guide for Artificial Brain Signal Research.International journal of biomaterials · 2026Article
- Experimental Assessment of Traction Force and Associated Fetal Brain Deformation in Vacuum-Assisted Delivery.Annals of biomedical engineering · 2025Article
- Brain-Mimicking Phantom for Photoablation and Visualization.... International Symposium on Medical Robotics. International Symposium on Medical Robotics · 2023Article
- Poro-viscoelastic material parameter identification of brain tissue-mimicking hydrogels.Frontiers in bioengineering and biotechnology · 2023Article
- 3D Extrusion Printing of Biphasic Anthropomorphic Brain Phantoms Mimicking MR Relaxation Times Based on Alginate-Agarose-Carrageenan Blends.ACS applied materials & interfaces · 2022Article
- Transport in the Brain Extracellular Space: Diffusion, but Which Kind?International journal of molecular sciences · 2022Review
- Multi-layer brain-mimicking phantom for replicating dura and pia membrane dimpling and rupture properties during neural interface implantation.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
There is a need to quantify and reproduce the mechanical behavior of brain tissue for a variety of applications from designing proper training models for surgeons to enabling research on the effectiveness of personal protective gear, such as football helmets. The mechanical response of several candidate phantom materials, including hydrogels and emulsions, was characterized and compared to porcine brain tissue under similar strains and strain rates. Some candidate materials were selected since their compositions were similar to brain tissue, such as emulsions that mimic the high content of lipids. Others, like silicone, were included since these are currently used as phantom materials. The mechanical response of the emulsion was closer to that of the native porcine brain tissue than the other candidates. The emulsions, created by addition of oil to a hydrogel, were able to withstand compressive strain greater than 40%. The addition of lipids in the emulsions also prevented the syneresis typically seen with hydrogel materials. This allowed the emulsion material to undergo freeze-thaw cycles with no significant change in their mechanical properties.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.