Evidence map›Paper›PMID 32064416›Full record

ArticleClinical practice and cases in emergency medicine2020

Administration of Nebulized Ketamine for Managing Acute Pain in the Emergency Department: A Case Series.

Jefferson Drapkin, Aidin Masoudi, Mahlaqa Butt, Rukhsana Hossain, Antonios Likourezos, Sergey Motov

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Clinical practice and cases in emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06752759 (Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting), which is not on this map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06752759 phase3recruitingnot on this mapstarted 2024, after this paper: background citation

Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting: A Midazolam-controlled Randomized Controlled Trial

TypeinterventionalSponsorTheresa Jacob, PhD, MPHRan2024 to 2027Enrolled40ConditionsSevere Depression, Moderate Depression, Ketamine, MidazolamArmsnebulized ketamine, nebulized midazolam
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Breathing new life into pain management: a systematic review of nebulised ketamine for analgesia.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Pain management in the emergency department: a clinical review.Clinical and experimental emergency medicine · 2021
    Article
  8. Nebulized ketamine in minor bronchoscopy procedures: A possibility.Journal of anaesthesiology, clinical pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jefferson DrapkinMaimonides Medical Center, Department of Emergency Medicine, Brooklyn, New York.
Aidin MasoudiMaimonides Medical Center, Department of Emergency Medicine, Brooklyn, New York.
Mahlaqa ButtMaimonides Medical Center, Department of Emergency Medicine, Brooklyn, New York.
Rukhsana HossainMaimonides Medical Center, Department of Emergency Medicine, Brooklyn, New York.
Antonios LikourezosMaimonides Medical Center, Department of Emergency Medicine, Brooklyn, New York.
Sergey MotovMaimonides Medical Center, Department of Emergency Medicine, Brooklyn, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ketamine administration in sub-dissociative doses in the emergency department (ED) results in effective pain relief in patients with acute traumatic and non-traumatic pain, chronic pain, and opioid-tolerant pain. This case series describes five adult ED patients who received nebulized ketamine for predominantly acute traumatic pain. Three patients received nebulized ketamine at 1.5 milligrams per kilogram (mg/kg) dose, one patient at 0.75 mg/kg, and one patient at 1 mg/kg. All five patients experienced a decrease in pain from the baseline up to 120 minutes. The inhalation route of ketamine delivery via breath-actuated nebulizer may have utility for managing pain in the ED.

Identifiers

PMID32064416
PMCPMC7012556

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.