ArticleScience advances2019
Direct conversion of carlactonoic acid to orobanchol by cytochrome P450 CYP722C in strigolactone biosynthesis.
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed, 164 citations in OpenAlex.
- Strigolactone-mediated architecture regulation and stress resilience: Insights and innovations for crop breeding.Journal of integrative plant biology · 2026Review
- Decoupling the Good from the Bad: Translational Strategies for Strigolactone Application in Agriculture.Biology · 2026Review
- Strigolactones as Integrative Regulators of Plant Adaptation and Resilience to Abiotic Stress.Plant, cell & environment · 2026Review
- Strigolactones in Plant Responses to Salt Stress: Regulatory Mechanisms and Application Potential.Plants (Basel, Switzerland) · 2026Review
- Article
- Modulating the strigolactone pathway to optimize tomato shoot branching for vertical farming.Journal of integrative plant biology · 2026Article
- Characterization and Quantification of Strigolactones in Root Exudates.Methods in molecular biology (Clifton, N.J.) · 2026Article
- From plant hormones to human health: progress and challenges in strigolactone biosynthetic structural diversity and antitumor effects.Frontiers in plant science · 2026Review
- LATERAL BRANCHING OXIDOREDUCTASE specificity for strigolactone branching inhibition in barley.Journal of experimental botany · 2025Article
- Mechanisms of Strigolactone-Regulated Abiotic Stress Responses in Plants.Plants (Basel, Switzerland) · 2025Review
- Manipulation of a strigolactone transporter in tomato confers resistance to the parasitic weed broomrape.Innovation (Cambridge (Mass.)) · 2025Article
- Genome-wide identification and comparative analysis of strigolactone biosynthetic genes in major solanaceous crops.PloS one · 2025Article
- Transcriptomic analysis reveals cloquintocet-mexyl-inducible genes in hexaploid wheat (Triticum aestivum L.).PloS one · 2025Article
- Barley is a potential trap crop for root parasitic broomrape weeds.Journal of pesticide science · 2024Article
- OsCYP706C2 diverts rice strigolactone biosynthesis to a noncanonical pathway branch.Science advances · 2024Article
- A dirigent of the ring for strigolactone stereochemistry.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Chromosome-scale pearl millet genomes reveal CLAMT1b as key determinant of strigolactone pattern and Striga susceptibility.Nature communications · 2024Article
- Insights into stereoselective ring formation in canonical strigolactone: Identification of a dirigent domain-containing enzyme catalyzing orobanchol synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Tomato Mutants Reveal Root and Shoot Strigolactone Involvement in Branching and Broomrape Resistance.Plants (Basel, Switzerland) · 2024Article
- Cracking the enigma: understanding strigolactone signalling in the rhizosphere.Journal of experimental botany · 2024Review
14 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Strigolactones (SLs) are carotenoid-derived phytohormones and rhizosphere signaling molecules for arbuscular mycorrhizal fungi and root parasitic weeds. Why and how plants produce diverse SLs are unknown. Here, cytochrome P450 CYP722C is identified as a key enzyme that catalyzes the reaction of BC-ring closure leading to orobanchol, the most prevalent canonical SL. The direct conversion of carlactonoic acid to orobanchol without passing through 4-deoxyorobanchol is catalyzed by the recombinant enzyme. By knocking out the gene in tomato plants, orobanchol was undetectable in the root exudates, whereas the architecture of the knockout and wild-type plants was comparable. These findings add to our understanding of the function of the diverse SLs in plants and suggest the potential of these compounds to generate crops with greater resistance to infection by noxious root parasitic weeds.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.