Evidence map›Paper›PMID 32064229›Full record

ArticleAnnals of global health2020

The Comparison of the Adverse Events of Pentavalent Vaccine and DPT Vaccine in 2-6 Months Infants in Iran: A National Study.

Zaher Khazaei, Ghobad Moradi, Seyed Mohsen Zahraei, Mohammad Mehdi Gouya, Elham Goodarzi, Fateme Yaghini, Daem Roshani

Open access · goldAbstract readComparative Study
In one paragraph

Article in Annals of global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Adverse Events Following Immunizations in Infants Under 1 Year of Age in Lorestan Province, Western Iran.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Zaher KhazaeiDepartment of Public Health, School of Medicine, Dezful University of Medical Sciences, Dezful, IR.ORCID 0000-0001-9265-9192
Ghobad MoradiSocial Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, IR.
Seyed Mohsen ZahraeiCenter for Communicable Diseases Control, Ministry of Health and Medical Education, Tehran, IR.
Mohammad Mehdi GouyaCenter for Communicable Diseases Control, Ministry of Health and Medical Education, Tehran, IR.
Elham GoodarziSocial Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, IR.
Fateme YaghiniCenter for Communicable Diseases Control, Ministry of Health and Medical Education, Tehran, IR.
Daem RoshaniDepartment of Epidemiology and Biostatistics, Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, IR.
Ministry of Health and Medical Education · IRKurdistan University of Medical Sciences · IRDezful University of Medical Sciences · IRLorestan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vaccination is the most remarkable intervention in public health and is an effective strategy in controlling infectious diseases among infants. Objectives: The aim of this study was to compare the adverse events of Pentavalent vaccine and DPT vaccine in two- to six-month-old infants in Iran. Methods: This is an analytical cross-sectional study in which healthy infants aged two to six months, having received DPT vaccine in 2013 and Pentavalent vaccine in 2015, were studied for any experienced adverse events related to these vaccines. Percentage, mean, standard deviation and chi-square tests were used to describe and analyze the data (p < 0.05). Findings: The results showed that 10,464 and 17,561 adverse events, which were associated with DPT vaccine and Pentavalent vaccine respectively, were recorded in the infants who received these vaccines throughout Iran. Mazandaran, Qazvin and Golestan provinces reported the highest number of adverse events, respectively (15.74%, 11.25%, and 9.12%). Moreover, Pentavalent vaccine seemed to have more recorded adverse events compared to DPT, high fever had the highest record rate for DPT vaccine (47.4%) and mild localized complications was the highest for Pentavalent vaccines (31.68%). There was a significant relationship between the kind of vaccine and the type of reaction, adverse event categorization and the country that produced the vaccine (p < 0.05). Conclusion: Severe localized adverse events including high fever, vomiting, diarrhea and restlessness seemed to be less in Pentavalent vaccine compared to DPT vaccine. Therefore, substituting Pentavalent vaccine for DPT vaccine in infants seems to reduce the adverse events among them.

Indexed as

CryingDiarrheaDiphtheria-Tetanus-Pertussis VaccineFemaleFeverGeographic MappingHaemophilus VaccinesHepatitis B VaccinesHospitalizationHumansInfantInjection Site ReactionIranMaleSeizures, FebrileVomitingdiphtheria-tetanus-acellular pertussis-Hib-hepatitis B vaccineDiphtheria-Tetanus-Pertussis VaccineHaemophilus VaccinesHepatitis B Vaccines

Identifiers

PMID32064229
PMCPMC7006586
OpenAlexW3003458995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.