Evidence map›Paper›PMID 32064225›Full record

ArticleHuman pathology (New York)2017

Persistent indolent pancolonic marginal zone lymphoma of MALT-type with plasmacytic differentiation - A rare post-transplant lymphoma?

Joanna M Chaffin, Natasha M Savage, Suash Sharma, Locke J Bryan, Mark Raffeld, Elaine S Jaffe

Open access · goldAbstract read
In one paragraph

Article in Human pathology (New York), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joanna M ChaffinDepartment of Pathology, Medical College of Georgia, Augusta University, 1120, 15th Street, Augusta, GA 30912, United States.
Natasha M SavageDepartment of Pathology, Medical College of Georgia, Augusta University, 1120, 15th Street, Augusta, GA 30912, United States.
Suash SharmaDepartment of Pathology, Medical College of Georgia, Augusta University, 1120, 15th Street, Augusta, GA 30912, United States.
Locke J BryanDepartment of Hematology/Oncology, Medical College of Georgia, Augusta University, 1120, 15th Street, Augusta, GA, 30912, United States.
Mark RaffeldCenter for Cancer Research, National Cancer Institute, Bethesda, MD, United States.
Elaine S JaffeCenter for Cancer Research, National Cancer Institute, Bethesda, MD, United States.
Augusta University · USNational Cancer Institute · US

Funding

Hematopathology DiagnosisZIABC011070 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JAFFE, ELAINE · 2009 to 2025
$14.5M
Intramural NIH HHS ZIA BC011070
6 · The paper itself

Abstract

Marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is associated with chronic inflammatory disorders. We present an indolent pancolonic MALT lymphoma occurring in a 39-year-old female with history of autoimmune hepatitis requiring liver transplant in 1997 and ulcerative colitis diagnosed in 2004. Random biopsies from a grossly unremarkable surveillance colonoscopy in 2015 revealed a dense monomorphic plasmacytoid infiltrate causing expansion of lamina propria without significant crypt infiltration or destruction. These cells were positive for CD79a and CD138 and showed lambda restriction; however, CD20, CD43, CD56, HHV8, and EBER were negative. A similar pancolonic infiltrate was identified in all prior colorectal biopsies from 2010 and 2012 upon retrospective review. Subsequent computed tomography of the abdomen revealed no bowel wall thickening nor enlarged lymph nodes. Bone marrow revealed involvement consistent with stage IV disease. Biopsies from 2010 and 2015 demonstrated clonal immunoglobulin gene rearrangement.

Identifiers

PMID32064225
PMCPMC7019211
OpenAlexW2726955840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.