Evidence map›Paper›PMID 32064024›Full record

ArticleOxidative medicine and cellular longevity2020

Effects of Diets Enriched in Linseed and Fish Oil on the Expression Pattern of Toll-Like Receptors 4 and Proinflammatory Cytokines on Gonadal Axis and Reproductive Organs in Rabbit Buck.

Laura Menchetti, Olimpia Barbato, Monica Sforna, Daniele Vigo, Simona Mattioli, Giulio Curone, Marco Tecilla, Federica Riva, Gabriele Brecchia

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Effect of Goji Berry (Animals : an open access journal from MDPI · 2021
    Article
  10. Article
  11. Review
  12. Impact of Goji Berries (Animals : an open access journal from MDPI · 2020
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Laura MenchettiDepartment of Veterinary Medicine, University of Perugia, 06123 Perugia, Italy.ORCID https://orcid.org/0000-0001-8500-7970
Olimpia BarbatoDepartment of Veterinary Medicine, University of Perugia, 06123 Perugia, Italy.ORCID https://orcid.org/0000-0003-0828-4610
Monica SfornaDepartment of Veterinary Medicine, University of Perugia, 06123 Perugia, Italy.ORCID https://orcid.org/0000-0002-7613-6540
Daniele VigoDepartment of Veterinary Medicine, University of Milano, 20133 Milano, Italy.ORCID https://orcid.org/0000-0002-6292-4992
Simona MattioliDepartment of Agricultural, Environmental and Food Science, University of Perugia, 06121 Perugia, Italy.ORCID https://orcid.org/0000-0001-5063-6785
Giulio CuroneDepartment of Veterinary Medicine, University of Milano, 20133 Milano, Italy.ORCID https://orcid.org/0000-0001-6352-0036
Marco TecillaDepartment of Veterinary Medicine, University of Milano, 20133 Milano, Italy.ORCID https://orcid.org/0000-0002-1214-8155
Federica RivaDepartment of Veterinary Medicine, University of Milano, 20133 Milano, Italy.ORCID https://orcid.org/0000-0002-1270-1627
Gabriele BrecchiaDepartment of Veterinary Medicine, University of Milano, 20133 Milano, Italy.ORCID https://orcid.org/0000-0003-4750-2801
University of Milan · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections of the genital tract can perturb the fertility in humans and animals. Pathogen recognition and activation of innate immunity onset through the pattern recognition receptor activation, such as Toll-like receptor 4 (TLR4), leading to the production of proinflammatory cytokines and mediators. TLR4 is expressed both on leukocytes and nonimmune cells. Rabbit TLR4 shows great similarity to its human counterpart. Moreover, the TLR4 signalling pathway could be modulated by long-chain polyunsaturated fatty acids (LC-PUFA). The objectives of this study were (i) to determine the expression levels of TLR4 and proinflammatory cytokines in the reproductive hypothalamic-gonadal axis of the male rabbit and (ii) to evaluate if the n-3 PUFA-enriched diets can modify their expression levels in the tissues and LC-PUFA profiles in seminal plasma. Fifteen rabbit bucks (

Indexed as

Animal FeedAnimalsDietEpididymisFatty Acids, Omega-3Fish OilsHypothalamusInflammationInterleukin-1betaLinseed OilMalePituitary GlandRabbitsSeminal VesiclesSpermatozoaTestisFatty Acids, Omega-3Fish OilsInterleukin-1betaLinseed OilToll-Like Receptor 4Tumor Necrosis Factor-alpha

Identifiers

PMID32064024
PMCPMC6996712
OpenAlexW3000765407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.