ArticlePakistan journal of medical sciences
Tirofiban hydrochloride sodium chloride injection combined with cardiovascular intervention in the treatment of Acute Myocardial Infarction.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 6 citations in OpenAlex.
- Efficacy, safety, and effect on platelet activation of the timing of administration of tirofiban in patients with acute ischemic stroke.American journal of translational research · 2025Article
- Effectiveness of different tirofiban administration times in patients with no-reflow myocardial infarction during percutaneous coronary intervention.Pakistan journal of medical sciences · 2024Article
- The Clinical Efficacy of Tirofiban Combined with Ticagrelor and Aspirin in Treating Acute Myocardial Infarction by Percutaneous Coronary Intervention and Its Effect on Patients' Cardiac Function.Journal of healthcare engineering · 2022Article
- Effects of Danhong injection combined with tirofiban on cardiac function, myocardial enzyme spectrum and lipoprotein-associated phospholipase A2 level in patients with acute myocardial infarction.American journal of translational research · 2022Article
- Clinical efficacy and safety of tirofiban combined with conventional dual antiplatelet therapy in ACS patients undergoing PCI.Scientific reports · 2021Article
- Effect of Tirofiban Injection on vascular endothelial function, cardiac function and inflammatory cytokines in patients with acute myocardial infarction after emergency Percutaneous Coronary Intervention.Pakistan journal of medical sciencesArticle
- Tirofiban hydrochloride sodium chloride injection combined with cardiovascular intervention in the treatment of Acute Myocardial Infarction.Pakistan journal of medical sciencesArticle
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the therapeutic effect of tirofiban hydrochloride sodium chloride injection combined with cardiovascular intervention on acute myocardial infarction.
methodsEighty-four patients with acute myocardial infarction who were treated in our hospital from April 2017 to May 2018 were divided into a control group and a treatment group using random number table method; there were 42 patients in each group. Both groups were given conventional treatment and were treated with aspirin and clopidogrel before and after operation. Moreover, the control group was treated with cardiovascular interventional therapy, while the treatment group was treated with tirofiban hydrochloride on the basis of cardiovascular interventional therapy. The patients were followed up to observe and compare the treatment condition and adverse reactions of the two groups.
resultsAfter percutaneous coronary intervention, the normal rate of myocardial perfusion in the treatment group was 92.86%, which was higher than 69.05% in the control group (P<0.05). After PCI, there were significant differences of thrombolysis in myocardial infarction (TIMI) flow Grade- 2 and 3 between the two groups (P<0.05). The improvement of platelet activation function in the treatment group was better than that in the control group (P<0.05). The incidence of adverse cardiac events in the treatment group was significantly lower than that in the control group (P<0.05).
conclusionTirofiban hydrochloride sodium chloride injection combined with cardiovascular intervention has a significant clinical effect in the treatment of acute myocardial infarction. It can effectively improve the blood perfusion and reduce the incidence of adverse cardiac events, suggesting a good effect on the prognosis of patients and high application value.
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