ArticlePakistan journal of medical sciences
The effects of maternal preeclampsia on inflammatory cytokines and clinical outcomes in premature infants.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Association Between DMFT Index, Dental Plaque, and Pre-eclampsia in Pregnant Women: A Case-Control Study.Clinical and experimental dental research · 2025Article
- The prognostic value of mean platelet volume levels in germinal matrix hemorrhage- intraventricular hemorrhage in preterm infants.Pakistan journal of medical sciences · 2025Article
- The predictive value of placental growth factor combined with uterine ultrasound arterial blood flow characteristics for preeclampsia.Pakistan journal of medical sciences · 2025Article
- Logistic regression analysis of risk factors for Respiratory Distress Syndrome in Late Preterm Infants.Pakistan journal of medical sciences · 2025Article
- Vitamin-D deficiency as a potential indicator of defective placentation in preeclampsia.Pakistan journal of medical sciences · 2024Article
- Risk factors associated with respiratory distress syndrome in late preterm infants.Pakistan journal of medical sciences · 2024Article
- Effect of hypertensive disorders of pregnancy on peripheral venous blood cell count in preterm infants with a gestational age of 28-34 weeks.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Modulation by antenatal therapies of cardiovascular and renal programming in male and female offspring of preeclamptic rats.Naunyn-Schmiedeberg's archives of pharmacology · 2021Article
- [Clinical features of very preterm small-for-gestational-age infants born due to severe preeclampsia].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Biomarkers of Inflammation and Redox Imbalance in Umbilical Cord in Pregnancies with and without Preeclampsia and Consequent Perinatal Outcomes.Oxidative medicine and cellular longevity · 2021Article
- Expression Level of IL-17 in Peripheral Blood of Patients with Late Pregnancy and Diagnosis of Maternal-Fetal Tolerance Based on Brain MRI Image Segmentation Algorithm.Pakistan journal of medical sciences · 2021Article
- Analysis of extrauterine growth retardation and related risk factors in 132 premature infants.Pakistan journal of medical sciencesArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effects of maternal preeclampsia on inflammatory cytokines and neonatal outcomes in premature infants.
methodsThe study included preterm infants born at gestational age ≤32 weeks in a tertiary university hospital between January 2016 and January 2017. The study group consisted of infants born from mothers with preeclampsia (Group-1), and the control group consisted of infants born from normotensive mothers (Group-2). Demographic characteristics and clinical outcomes of the infants were recorded. IL-6, IL-8, IL-10, and TNF-α cytokine levels were measured from umbilical cord blood samples.
resultsA total of 108 infants were included in the study, of which 34 were in the Group-1 and 74 in the Group-2. Gestational ages (29 vs 30 weeks) of the infants in both groups were similar. There was no significant difference between the cytokine levels of infants with and without preeclampsia. The rate of small for gestational age, retinopathy of prematurity, intraventricular hemorrhage, necrotizing enterocolitis, neutropenia, and thrombocytopenia were significantly higher at the infants with preeclampsia.
conclusionMaternal preeclampsia leads to an increase at the neonatal morbidities in premature infants without causing a significant alteration at the cytokine levels in cord blood.
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