ArticlePakistan journal of medical sciences
Screening, diagnosis and genetic study of breast cancer patients in Pakistan.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 13 citations in OpenAlex.
- Value of Radiomics Based on DCE-MRI in distinguishing benign and malignant breast lesions: Predicting Histological Grade and Lymph Node Metastasis of Breast Cancer.Pakistan journal of medical sciences · 2026Article
- Efficacy of Mindfulness-based complementary alternative therapy on physical and mental stress, self-efficacy, and coping styles of patients undergoing breast cancer surgery.Pakistan journal of medical sciences · 2026Article
- Effects of sentinel lymph node biopsy combined with breast-conserving surgery on surgical-related indexes, serum TPA level and recurrence rate in patients with early breast cancer.Pakistan journal of medical sciences · 2025Article
- Retrospective analysis of efficacy and safety of recombinant human Rh-endostatinstatin combined with concurrent radiotherapy for cervical cancer.Pakistan journal of medical sciences · 2024Article
- Unraveling the Role ofPakistan journal of medical sciences · 2024Article
- Body mass index and altered lipid profile as major risk markers for breast cancer progression: a cross-sectional study of postmenopausal women in Pakistan.BMC women's health · 2024Article
- Breast cancer in a teenage girl with BRCA mutation: A case report from a low middle-income country.International journal of surgery case reports · 2022Article
- Article
- Correlation between the risk of lymph node metastasis and the expression of GBP1 in breast cancer patients.Pakistan journal of medical sciencesArticle
- Two hours method for RNA and DNA co-extraction from blood of coronary artery disease patients: Fast, simple and economical technique.Pakistan journal of medical sciencesArticle
- c.151dup variant inPakistan journal of medical sciencesArticle
- Effect of different chemotherapy schemes on early-stage breast cancer patients with Low HER-2 expression.Pakistan journal of medical sciencesArticle
- Association of axillary node status with clinicopathological characteristics and expression of EZH2 and CD44 in primary breast ductal carcinoma.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the role of variants in
methodsThe present study involved screening of 5000 women for breast cancer. 302 women were diagnosed with breast cancer. Using Sanger sequencing, DNA extracted from peripheral blood of 100 patients was screened for disease causing variants in the
resultsAnalysis of sequenced data revealed two frame shift (Gly312Trpfs*8, Ala322Glyfs*4), six missense (p.Glu362Lys, p.Lys651Arg, p.Asp693Asn, p.Pro871Leu, p.Glu1134Lys, p.Lys1183Arg), four synonymous (p.Thr327Thr, p.Ser694Ser, p.His771His, p.Gln1135Gln), and two intronic variants (g.75407T>C, g.75401_75401delT) in the patients.
conclusionThe present investigation showed that variations in
Indexed as
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