Evidence map›Paper›PMID 32063889›Full record

ArticleFrontiers in microbiology2019

NSC 18725, a Pyrazole Derivative Inhibits Growth of Intracellular

Garima Arora, Gagandeep, Assirbad Behura, Tannu Priya Gosain, Ravi P Shaliwal, Saqib Kidwai, Padam Singh, Shamseer Kulangara Kandi, Rohan Dhiman, Diwan S Rawat and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Garima AroraTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad, India.
GagandeepDepartment of Chemistry, Faculty of Science, University of Delhi, New Delhi, India.
Assirbad BehuraLaboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela, India.
Tannu Priya GosainTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad, India.
Ravi P ShaliwalTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad, India.
Saqib KidwaiTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad, India.
Padam SinghTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad, India.
Shamseer Kulangara KandiDepartment of Chemistry, Faculty of Science, University of Delhi, New Delhi, India.
Rohan DhimanLaboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela, India.
Diwan S RawatDepartment of Chemistry, Faculty of Science, University of Delhi, New Delhi, India.
Ramandeep SinghTuberculosis Research Laboratory, Translational Health Science and Technology Institute, Faridabad, India.
Translational Health Science and Technology Institute · INUniversity of Delhi · INNational Institute of Technology Rourkela · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing incident rates of drug-resistant tuberculosis (DR-TB) is a global health concern and has been further complicated by the emergence of extensive and total drug-resistant strains. Identification of new chemical entities which are compatible with first-line TB drugs, possess activity against DR-, and metabolically less active bacteria is required to tackle this epidemic. Here, we have performed phenotypic screening of a small molecule library against

Indexed as

autophagyMycobacterium tuberculosisNSC-18725phenotypic screeningpyrazole scaffold

Identifiers

PMID32063889
PMCPMC6999026
OpenAlexW3003988713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.