ArticleFrontiers in psychiatry2019
The Rage Attack Questionnaire-Revised (RAQ-R): Assessing Rage Attacks in Adults With Tourette Syndrome.
Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Systematic Literature Review on Public Health Impacts of Persistent Tic Disorders: Education and Employment.Clinical child and family psychology review · 2026Pooled it
- Explosive Outbursts in Children With Tourette Syndrome: A Closer Look at Family Functioning Dimensions.Child psychiatry and human development · 2026Article
- "It Was Like They'd Lit a Fuse": A Mixed-Methods Investigation Into Rage.Aggressive behavior · 2026Article
- Abnormalities of iron homeostasis and the dopaminergic system in Tourette syndrome revealed by 7T MRI and PET.Brain communications · 2025Article
- Validation and assessment of the self-injurious behavior scale for tic disorders (SIBS-T).Scientific reports · 2024Article
- Addressing co-occurring conditions in behavioural therapy for tic disorders: a review and guideline.European child & adolescent psychiatry · 2024Review
- Sleep and chronotype in adults with persistent tic disorders.Journal of clinical psychology · 2022Article
- European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part I: assessment.European child & adolescent psychiatry · 2022Review
- Tourette syndrome research highlights from 2020.F1000Research · 2022Review
- Validation of the Rage Attack Questionnaire-Revised (RAQ-R) in a Mixed Psychiatric Population.Frontiers in psychiatry · 2021Article
- Gilles de la Tourette Syndrome: advice in the times of COVID-19.F1000Research · 2020Article
- The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols in the Treatment of Adults With Chronic Tic Disorders.Frontiers in psychiatry · 2020Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlthough defined by the presence of tics, most patients with Gilles de la Tourette syndrome (TS) also suffer from different psychiatric disorders. While much is known about clinical characteristics of comorbidities such as attention deficit/hyperactivity disorder (ADHD), obsessive compulsive disorder (OCD), depression, and anxiety disorders, only very little is known about rage attacks. Most of this data is based on small studies in children. Until today no larger studies have been performed in adults with TS-most likely because of the lack of validated instruments. The aim of this study was to develop a new assessment and investigate rage attacks in a large sample of adults with TS and healthy individuals. MATERIALS AND
methodsBased on a parent questionnaire for children with TS, we generated 27 items for a revised version of a rage attack questionnaire (RAQ-R) and tested factor structure, internal consistency, as well as convergent and discriminant validity. We used an online survey and included 127 patients with TS and 645 control subjects. In addition to the RAQ-R, we used several other self-assessments to measure tic severity, quality of life, as well as several psychiatric symptoms including ADHD, OCD, depression, anxiety, and impulsivity.
resultsBased on expert option and statistical analyses [including item-total correlation, skewness, inter-item correlation, and principal component analysis (PCA)], we performed an item reduction resulting in a final, 22-items version of the RAQ-R (range, 0-66). Investigating internal consistency, discriminant validity, test reliability, and factor structure, the RAQ-R demonstrated good to excellent quality criteria. As assessed by RAQ-R, rage attacks were significantly more common in patients with TS compared to controls (p < 0.001). Rage attacks could be clearly differentiated from the phenomenon of impulsivity. Although rage attacks occurred more often in individuals with ADHD, they were also found in patients with "TS only", independently from comorbid ADHD, impulsivity, and OCD. Rage attacks were found to significantly influence patients' quality of life.
conclusionsThus, from our data based on a large sample it is suggested that rage attacks represent a discrete comorbidity in adults with TS.
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