Evidence map›Paper›PMID 32063362›Full record

ArticleBiochemical and biophysical research communications2020

Lens aquaporins function as peroxiporins to facilitate membrane transport of hydrogen peroxide.

Kulandaiappan Varadaraj, S Sindhu Kumari

Open access · greenAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 47 citations in OpenAlex.

  1. CatExperimental eye research · 2026
    Article
  2. Article
  3. Article
  4. AQP5 Regulates Corneal Nerve Distribution Through NETRIN-1 and SLIT3.Investigative ophthalmology & visual science · 2025
    Article
  5. Functional characterization of CatExperimental eye research · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Classification and Gene Structure of Aquaporins.Advances in experimental medicine and biology · 2023
    Article
  17. Methods for studying mammalian aquaporin biology.Biology methods & protocols · 2023
    Review
  18. Article
  19. Insight into the Mammalian Aquaporin Interactome.International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kulandaiappan VaradarajPhysiology and Biophysics, Renaissance School of Medicine, Stony Brook University, NY, USA. Electronic address: kulandaiappan.varadaraj@stonybrook.edu.
S Sindhu KumariPhysiology and Biophysics, Renaissance School of Medicine, Stony Brook University, NY, USA.
Stony Brook School · US

Funding

Roles of Lens Aquaporins and GPX1 in Hydrogen Peroxide Balance, Homeostasis, and AgingR01EY033346 · NEI · STATE UNIVERSITY NEW YORK STONY BROOK · PI Kulandaiappan Varadaraj · 2022 to 2026
$1.9M
Role of aquaporins in mammalian lens development,transparency and homeostasisR01EY026155 · NEI · STATE UNIVERSITY NEW YORK STONY BROOK · PI VARADARAJ, KULANDAIAPPAN · 2016 to 2019
$1.6M
NEI NIH HHS R01 EY026155NEI NIH HHS R01 EY033346
6 · The paper itself

Abstract

High levels of reactive oxygen species such as hydrogen peroxide (H

Indexed as

AnimalsAquaporin 1Aquaporin 5AquaporinsBiological TransportCell LineCell MembraneDogsEye ProteinsHumansHydrogen PeroxideLens, CrystallineMadin Darby Canine Kidney CellsMice, Inbred C57BLaquaporin 0Aquaporin 1Aquaporin 5aquaporin 8AquaporinsEye ProteinsHydrogen PeroxideAQP1AQP5AQP8H(2)O(2)Lens AQP0Peroxiporin

Identifiers

PMID32063362
PMCPMC7085977
OpenAlexW3005570748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.