Evidence map›Paper›PMID 32063120›Full record

ArticleJournal of the American Heart Association2020

Sex Differences in Long-Term Outcomes in Patients With Deferred Revascularization Following Fractional Flow Reserve Assessment: International Collaboration Registry of Comprehensive Physiologic Evaluation.

Masahiro Hoshino, Rikuta Hamaya, Yoshihisa Kanaji, Yoshinori Kanno, Masahiro Hada, Masao Yamaguchi, Yohei Sumino, Hidenori Hirano, Tomoki Horie, Eisuke Usui and 37 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Age-related changes in the coronary microcirculation influencing the diagnostic performance of invasive pressure-based indices and long-term patient prognosis.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Outcomes of Fractional Flow Reserve-guided Deferred Coronary Revascularization.Heart views : the official journal of the Gulf Heart Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

47 authors.

Masahiro HoshinoDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Rikuta HamayaDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Yoshihisa KanajiDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Yoshinori KannoDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Masahiro HadaDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Masao YamaguchiDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Yohei SuminoDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Hidenori HiranoDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Tomoki HorieDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Eisuke UsuiDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Tomoyo SugiyamaDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Tadashi MuraiDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.
Tetsumin LeeDepartment of Cardiovascular Medicine Tokyo Medical and Dental University Tokyo Japan.
Taishi YonetsuDepartment of Cardiovascular Medicine Tokyo Medical and Dental University Tokyo Japan.
Joo Myung LeeDivision of Cardiology Department of Internal Medicine Heart Vascular Stroke Institute Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea.
Ki Hong ChoiDivision of Cardiology Department of Internal Medicine Heart Vascular Stroke Institute Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea.
Doyeon HwangDepartment of Internal Medicine and Cardiovascular Center Seoul National University Hospital Seoul Korea.
Jonghanne ParkDepartment of Internal Medicine and Cardiovascular Center Seoul National University Hospital Seoul Korea.
Ji-Hyun JungSejong General Hospital Sejong Heart Institute Bucheon Korea.
Hyung Yoon KimDepartment of Cardiovascular Medicine Chonnam National University Hospital Gwangju Korea.
Hae Won JungDepartment of Cardiology Daegu Catholic University Medical Center Daegu Korea.
Yun-Kyeong ChoDepartment of Medicine Keimyung University Dongsan Medical Center Daegu South Korea.
Hyuck-Jun YoonDepartment of Medicine Keimyung University Dongsan Medical Center Daegu South Korea.
Young Bin SongDivision of Cardiology Department of Internal Medicine Heart Vascular Stroke Institute Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea.
Joo-Yong HahnDivision of Cardiology Department of Internal Medicine Heart Vascular Stroke Institute Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea.
Joon-Hyung DohDepartment of Medicine Inje University Ilsan Paik Hospital Goyang South Korea.
Chang-Wook NamDepartment of Medicine Keimyung University Dongsan Medical Center Daegu South Korea.
Eun-Seok ShinDivision of Cardiology Ulsan Hospital Ulsan Korea.
Seung-Ho HurDepartment of Medicine Keimyung University Dongsan Medical Center Daegu South Korea.
Hernán Mejía-RenteríaCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Francesco LauriCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Sonoka GotoCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Fernando MacayaCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Angela McInerneyCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Giacomo GravinaCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Rafael VeraCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Nieves GonzaloCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Pilar Jimenez-QuevedoCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Ivan Nuñez-GilCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Pablo SalinasCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Luis Nombela-FrancoCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Maria Del TrigoCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Antonio Fernández-OrtizCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Carlos MacayaCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Bon-Kwon KooDepartment of Internal Medicine and Cardiovascular Center Seoul National University Hospital Seoul Korea.
Javier EscanedCardiovascular Institute Hospital Clinico San Carlos Madrid Spain.
Tsunekazu KakutaDivision of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Sex-specific differences may influence prognosis after deferred revascularization following fractional flow reserve (FFR) measurement. This study sought to investigate the sex differences in long-term prognosis of patients with deferred revascularization following FFR assessment. Methods and Results A total of 879 patients (879 vessels) with deferred revascularization with FFR >0.75 who underwent FFR and coronary flow reserve measurements were enrolled from 3 countries (Korea, Japan, and Spain). Long-term outcomes were assessed in 649 men and 230 women by the patient-oriented composite outcome (POCO, a composite of any death, any myocardial infarction, and any revascularization). We applied inverse-probability weighting based on propensity scores to account for differences at baseline between women and men (age, hyperlipidemia, diabetes mellitus, diameter stenosis, lesion length, multivessel disease, FFR, coronary flow reserve. The median follow-up duration was 1855 days (745-1855 days). Median FFR values were 0.88 (0.83-0.93) in men and 0.89 (0.85-0.94) in women, respectively. The occurrences of POCO were significantly high in men compared with that in women (10.5% versus 4.2%,

Indexed as

Myocardial RevascularizationRegistriesCoronary Artery DiseaseFemaleFractional Flow Reserve, MyocardialHumansJapanMaleRepublic of KoreaSex FactorsSpainSurvival AnalysisTime FactorsTreatment Outcomecoronary flow reservefractional flow reservemicrovascular dysfunctionsex differences

Identifiers

PMID32063120
PMCPMC7070212

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.