ArticleJournal of neurology2020
Outcome of patients with large vessel occlusion in the anterior circulation and low NIHSS score.
Article in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Trial
- The effect of occlusion location and technique in mechanical thrombectomy for minor stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- Medical and endovascular treatment for acute large vessel occlusion with mild stroke: a real-world nationwide registry.Journal of neurointerventional surgery · 2026Article
- Comparable efficacy and safety of bridging therapy versus direct mechanical thrombectomy in anterior circulation large vessel occlusion stroke.American journal of translational research · 2026Article
- Effectiveness and Safety of Endovascular Treatment in Large Vessel Occlusion Stroke with an NIHSS Score of ≤5 Exhibiting Predominant Cortical Signs.Biomedicines · 2025Article
- Association of blood pressure parameters on early neurological deterioration in patients with mild stroke and large vessel occlusion following medical management.BMC neurology · 2025Article
- Evaluating the effectiveness of intravenous alteplase in patients with minor non-disabling stroke and severe large vessel stenosis: a retrospective study.Frontiers in neurology · 2025Article
- Impact of dual antiplatelet therapy on patients with minor stroke after thrombolysis: a systematic review and meta-analysis.BMJ neurology open · 2025Article
- Prevalence and outcomes of mild stroke patients undergoing reperfusion therapy: A meta-analysis and SAFE recommendations for optimal management.Journal of central nervous system disease · 2025Article
- Intravenous thrombolysis versus antiplatelet therapy in minor stroke patients with large vessel occlusion.CNS neuroscience & therapeutics · 2023Article
- Mechanical Thrombectomy in the Late Presentation of Anterior Circulation Large Vessel Occlusion Stroke: A Guideline From the Society of Vascular and Interventional Neurology Guidelines and Practice Standards Committee.Stroke (Hoboken, N.J.) · 2023Article
- Effectiveness and safety of EVT in patients with acute LVO and low NIHSS.Frontiers in neurology · 2022Article
- Relationship Between Muscle Cramps and Diabetic Retinopathy in Patients with Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Cognitive Status Predicts Return to Functional Independence After Minor Stroke: A Decision Tree Analysis.Frontiers in neurology · 2022Article
- Biomarker of early neurological deterioration in minor stroke and proximal large vessel occlusion: A pilot study.Frontiers in neurology · 2022Article
- Recanalization Therapy for Acute Ischemic Stroke with Large Vessel Occlusion: Where We Are and What Comes Next?Translational stroke research · 2021Review
- Predictors of Early Neurological Deterioration in Stroke Due to Vertebrobasilar Occlusion.Frontiers in neurology · 2021Article
- Endovascular therapy in patients with large vessel occlusion due to cardioembolismTherapeutic advances in neurological disorders · 2021Article
- Intravenous Thrombolysis Benefits Mild Stroke Patients With Large-Artery Atherosclerosis but No Tandem Steno-Occlusion.Frontiers in neurology · 2020Article
- Relationship between Uric Acid Level and Severity of Acute Primary Cerebral Infarction: A Cross-Sectional Study.BioMed research international · 2020Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOptimal management of patients with large vessel occlusion (LVO) and low NIHSS score is unknown, which was the aim to investigate in this study.
methodsThis is a retrospective analysis of a prospective single tertiary care centre 14-year cohort of patients with LVO in the anterior circulation and NIHSS score ≤ 5 on admission. Outcome was analysed according to primary intended therapy.
resultsAmong 185 patients (median age 67.4 years), 52.4% received primary conservative therapy (including 26.8% secondary reperfusion in case of secondary neurological deterioration), 12.4% IV thrombolysis (IVT) only and 35.1% primary endovascular therapy (EVT). 95 (51.4%) patients experienced neurological deterioration until 3 months. Primary-IVT-only and primary-EVT compared to conservative-therapy patients had better 3 months' outcome (54.5% vs. 30.8%:
conclusionsOur data indicate that primary IVT and/or EVT may be better than primary conservative therapy in patients with LVO in the anterior circulation and low NIHSS score. Furthermore, primary EVT was better than secondary EVT in case of neurological deterioration. There is an unmet need for RCTs to find the optimal therapy for this patient group.
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