Evidence map›Paper›PMID 32062423›Full record

SynthesisChild abuse & neglect2020

Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire.

Kathryn L Humphreys, Joelle LeMoult, John G Wear, Hannah A Piersiak, Aaron Lee, Ian H Gotlib

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in Child abuse & neglect, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 242 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
242citing papers in PubMed, 7 pooled it
23.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

242 citing papers in PubMed, 7 syntheses or guidelines pooled it, 517 citations in OpenAlex.

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  4. Childhood maltreatment and the risk of eating disorders: a meta-analysis of observational studies.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2025
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  19. Childhood Trauma and Aggression: The Role of Epistemic Trust.Journal of child & adolescent trauma · 2026
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182 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Kathryn L HumphreysVanderbilt University, United States. Electronic address: k.humphreys@vanderbilt.edu.
Joelle LeMoultUniversity of British Columbia, Canada.
John G WearWestern University of Health Sciences, United States.
Hannah A PiersiakVanderbilt University, United States.
Aaron LeeCornell University, United States.
Ian H GotlibStanford University, United States.
Vanderbilt University · USCornell University · USStanford University · USUniversity of British Columbia · CAWestern University of Health Sciences · US

Funding

Psychobiological Mechanisms Underlying the Association Between Early Life Stress and Depression Across AdolescenceR37MH101495 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB · 2018 to 2026
$6.6M
Telomere Length as a Mediator Between Early Life Stress and Child Health OutcomesF32MH107129 · NIMH · STANFORD UNIVERSITY · PI HUMPHREYS, KATHRYN LEIGH · 2015 to 2017
$169k
CIHR 389703NIMH NIH HHS F32 MH107129NIMH NIH HHS R37 MH101495
6 · The paper itself

Abstract

backgroundResearchers have documented that child maltreatment is associated with adverse long-term consequences for mental health, including increased risk for depression. Attempts to conduct meta-analyses of the association between different forms of child maltreatment and depressive symptomatology in adulthood, however, have been limited by the wide range of definitions of child maltreatment in the literature.

objectiveWe sought to meta-analyze a single, widely-used dimensional measure of child maltreatment, the Childhood Trauma Questionnaire, with respect to depression diagnosis and symptom scores. PARTICIPANTS AND

setting192 unique samples consisting of 68,830 individuals.

methodsWe explored the association between total scores and scores from specific forms of child maltreatment (i.e., emotional abuse, physical abuse, sexual abuse, emotional neglect, and physical neglect) and depression using a random-effects meta-analysis.

resultsWe found that higher child maltreatment scores were associated with a diagnosis of depression (g = 1.07; 95 % CI, 0.95-1.19) and with higher depression symptom scores (Z = .35; 95 % CI, .32-.38). Moreover, although each type of child maltreatment was positively associated with depression diagnosis and scores, there was variability in the size of the effects, with emotional abuse and emotional neglect demonstrating the strongest associations.

conclusionsThese analyses provide important evidence of the link between child maltreatment and depression, and highlight the particularly larger association with emotional maltreatment in childhood.

Indexed as

Adult Survivors of Child AbuseChildChild AbuseChild, PreschoolDepressionFemaleHumansMaleSurveys and QuestionnairesAbuseChild maltreatmentDepressionMeta-analysisNeglect

Identifiers

PMID32062423
PMCPMC7081433
OpenAlexW3005921704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.