Evidence map›Paper›PMID 32062309›Full record

ArticleClinical neurology and neurosurgery2020

Risk factors for seizures after intracerebral hemorrhage: Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) Study.

Soo Young Kwon, Ahmed Z Obeidat, Padmini Sekar, Charles J Moomaw, Jennifer Osborne, Fernando D Testai, Sebastian Koch, Merredith R Lowe, Stacie Demel, Elisheva R Coleman and 2 more

Open access · greenAbstract read
In one paragraph

Article in Clinical neurology and neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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  16. Effect of Primary Prophylactic Antiseizure Medication for Seizure Prevention Following Intracerebral Hemorrhage in the ERICH Study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Soo Young KwonDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, 35249, USA. Electronic address: skwon@uabmc.edu.
Ahmed Z ObeidatDepartment of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address: aobeidat@mcw.edu.
Padmini SekarDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: sekarpc@ucmail.uc.edu.
Charles J MoomawDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: moomawcj@roadrunner.com.
Jennifer OsborneDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: osbornjr@ucmail.uc.edu.
Fernando D TestaiDepartment of Neurology and Rehabilitation, University of Illinois at Chicago, Chicago, IL, USA. Electronic address: testai@uic.edu.
Sebastian KochDepartment of Neurology, University of Miami, Miami, FL, USA. Electronic address: skoch@med.miami.edu.
Merredith R LoweDepartment of Neurology, University of Miami, Miami, FL, USA. Electronic address: mlowe@med.miami.edu.
Stacie DemelDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: stacie.demel@uc.edu.
Elisheva R ColemanDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: elisheva.coleman@uc.edu.
Matthew FlahertyDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: matthew.flaherty@uc.edu.
Daniel WooDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: daniel.woo@uc.edu.
University of Cincinnati · USUniversity of Miami · USMedical College of Wisconsin · USUniversity of Alabama at Birmingham · USUniversity of Illinois Chicago · US

Funding

Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH)U01NS069763 · NINDS · UNIVERSITY OF CINCINNATI · PI ANDERSON, CHRISTOPHER DAVID, DEMEL, STACIE · 2010 to 2024
$34.2M
Cerebrovascular Fellowship Training ProgramT32NS047996 · NINDS · UNIVERSITY OF CINCINNATI · PI Joseph Paul Broderick, Stacie Demel · 2006 to 2026
$3.7M
NINDS NIH HHS T32 NS047996NINDS NIH HHS U01 NS069763
6 · The paper itself

Abstract

objectiveWe aimed to identify risk factors for seizures after intracerebral hemorrhage, and to validate the prognostic value of the previously reported CAVE score (0-4 points: cortical involvement, age <65, volume >10 mL, and early seizures within 7 days of hemorrhage). PATIENTS AND

methodsEthnic/Racial Variations of Intracerebral Hemorrhage (ERICH) was a prospective study of spontaneous intracerebral hemorrhage. We included patients who did not have a prior history of seizure and survived to discharge. Univariate analysis and multiple logistic regression modeling were used to identify risk factors for seizure.

resultsFrom 2010-2015, 3000 cases were recruited, and 2507 patients were included in this study. Seizures after hospital discharge developed in 77 patients 3.1 %). Patients with lobar (cortical) hemorrhage (OR 3.0, 95 % CI 1.8-5.0), larger hematoma volume (OR 1.5 per cm

conclusionsLobar hemorrhage, larger hematoma volume, younger age, and surgical evacuation are strongly associated with the development of seizures. We validated the CAVE score in a multi-ethnic population, and found the CAVS score to have similar predictive value while representing the current practice of AED use.

Indexed as

Cerebral CortexAgedAge FactorsAnticonvulsantsCerebral HemorrhageEpilepsyEthnicityFemaleHumansLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrognosisProspective StudiesAnticonvulsantsAntiepileptic drugCAVE scoreEpilepsyIntracerebral hemorrhagePost-stroke complicationSeizure

Identifiers

PMID32062309
PMCPMC7183434
OpenAlexW3004632851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.