ArticleSchizophrenia research2020
P50 inhibitory sensory gating in schizophrenia: analysis of recent studies.
Article in Schizophrenia research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Neurophysiological alterations during sensory processing in autism - a meta-analysis.European child & adolescent psychiatry · 2026Pooled it
- Detecting electrophysiological alterations in psychiatric disorders through event-related microstates: a systematic review.Frontiers in psychiatry · 2025Pooled it
- Cortical Auditory Processing of Simple Stimuli Is Altered in Autism: A Meta-analysis of Auditory Evoked Responses.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Pooled it
- Neurophysiology of Sleep-Deprivation Part 1: Effects of Sleep-Deprivation on Event-Related Potentials (ERPs)-Systematic and Mechanistic Review.Journal of clinical medicine · 2026Review
- Multimodal EEG-MRI Neuroimaging in Schizophrenia-A Systematic and Mechanistic Review.Journal of clinical medicine · 2026Review
- Schizophrenia and sensory modulation problems: the relationship between severity, depression and sensory responsiveness.BMC psychiatry · 2025Article
- Circadian rhythmicity in prepulse inhibition of the acoustic startle response: A study of chronotype and time-of-day effects in young healthy adults.Journal of psychopharmacology (Oxford, England) · 2025Article
- N-Methyl-d-Aspartate Receptor Antibody and Sensory Gating Deficits in Non-smoking, Minimal Antipsychotic Medication Exposure, and First-Episode Patients With Schizophrenia.Schizophrenia bulletin · 2025Article
- Article
- ERP correlates of agency processing in joint action.Social cognitive and affective neuroscience · 2025Article
- Association of P50 with social function, but not with cognition in patients with first-episode schizophrenia.European archives of psychiatry and clinical neuroscience · 2024Article
- Intrinsic Infant Hippocampal Function Supports Inhibitory Processing.Developmental psychobiology · 2024Article
- Study Protocol: Global Research Initiative on the Neurophysiology of Schizophrenia (GRINS) project.BMC psychiatry · 2024Article
- Developmental Windows for Effects of Choline and Folate on Excitatory and Inhibitory Neurotransmission During Human Gestation.Developmental psychobiology · 2024Article
- A spectrum of altered non-rapid eye movement sleep in schizophrenia.bioRxiv : the preprint server for biology · 2023Article
- Early auditory processing dysfunction in schizophrenia: Mechanisms and implications.Neuroscience and biobehavioral reviews · 2023Review
- Understanding translational research in schizophrenia: A novel insight into animal models.Molecular biology reports · 2023Review
- People with high schizotypy experience more illusions in the Pattern Glare Test: Consistent with the hyperexcitability hypothesis.The European journal of neuroscience · 2023Article
- Sleep Problems in Preschoolers With Autism Spectrum Disorder Are Associated With Sensory Sensitivities and Thalamocortical Overconnectivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Prenatal choline, cannabis, and infection, and their association with offspring development of attention and social problems through 4 years of age.Psychological medicine · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
introductionInhibitory sensory gating of the P50 cerebral evoked potential to paired auditory stimuli (S1, S2) is a widely used paradigm for the study of schizophrenia and related conditions. Its use to measure genetic, treatment, and developmental effects requires a metric with more stable properties than the simple ratio of the paired responses.
methodsThis study assessed the ratio P50
resultsAcross the 27 studies encompassing 1179 schizophrenia patients and 1091 healthy controls, both P50
conclusionBoth methods detect an abnormality of cerebral inhibition in schizophrenia with high significance across multiple independent laboratories. The normal distribution of P50
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.