ArticleAddiction (Abingdon, England)2020
Associations between neighborhood-level factors and opioid-related mortality: A multi-level analysis using death certificate data.
Article in Addiction (Abingdon, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Association of Food Insecurity and Risk of Mortality: A Systematic Review and Meta-Analysis of Large-Scale Cohorts.Nutrients · 2025Pooled it
- Association of social determinants of health with opioid misuse among individuals with common psychiatric conditions.Psychiatry research communications · 2026Article
- Substance use treatment and overdose patterns in high and low social vulnerability counties: a trends analysis in New Jersey from 2014-2022.Addictive behaviors reports · 2026Article
- Spatial-Structural Mechanisms of Racialized Disparities in Overdose Mortality: A Spatiotemporal Analysis.Journal of racial and ethnic health disparities · 2026Article
- Associations of community socioeconomic factors and opioid use disorder across an urban-to-rural spectrum in Pennsylvania: an electronic health record-based case-control study.Social psychiatry and psychiatric epidemiology · 2025Article
- Multilevel Factors Associated With Hospitalizations in the First-Year Postpartum Among Persons With Opioid Use Disorder.Substance use & addiction journal · 2025Article
- Spatiotemporal Analysis of Fentanyl-Associated Overdose Deaths in Chicago, IL, USA.Journal of urban health : bulletin of the New York Academy of Medicine · 2025Article
- Risk factors for persistent fatal opioid-involved overdose clusters in Massachusetts 2011-2021: a spatial statistical analysis with socio-economic, accessibility, and prescription factors.BMC public health · 2024Article
- Development and validation of a community-level social determinants of health index for drug overdose deaths in the HEALing Communities Study.Journal of substance use and addiction treatment · 2024Article
- Construction of multilevel statistical models in health research: Foundations and generalitiesBiomedica : revista del Instituto Nacional de Salud · 2023Article
- The association between community social vulnerability and prescription opioid availability with individual opioid overdose.Drug and alcohol dependence · 2023Article
- Opioid Use Disorder and Overdose in the First Year Postpartum: A Rapid Scoping Review and Implications for Future Research.Maternal and child health journal · 2023Article
- Predicting U.S. county opioid poisoning mortality from multi-modal social media and psychological self-report data.Scientific reports · 2023Article
- An external exposome-wide association study of opioid use disorder diagnosed during pregnancy in Florida.The Science of the total environment · 2023Article
- Food insecurity, chronic pain, and use of prescription opioids.SSM - population health · 2021Article
- A Vulnerability Assessment for a Future HIV Outbreak Associated With Injection Drug Use in Illinois, 2017-2018.Frontiers in sociology · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
aimTo identify associations between opioid-related mortality and neighborhood-level risk factors.
designCross-sectional study.
settingMassachusetts, USA.
participantsUsing 2011-14 Massachusetts death certificate data, we identified opioid-related (n = 3089) and non-opioid-related premature deaths (n = 8729). MEASUREMENTS: The independent variables consisted of four sets of neighborhood-level factors: (1) psychosocial, (2) economic, (3) built environment and (4) health-related. At the individual level we included the following compositional factors: age at death, sex, race/ethnicity, marital status, education, veteran status and nativity. The primary outcome of interest was opioid-related mortality.
findingsMulti-level models identified number of social associations per 10 000 [odds ratio (OR) = 0.84, P = 0.002, 95% confidence interval (CI) = 0.75-0.94] and number of hospital beds per 10 000 (OR = 0.78, P < 0.001, 95% CI = 0.68-0.88) to be inversely associated with opioid-related mortality, whereas the percentage living in poverty (OR = 1.01, P = 0.008, 95% CI = 1.00-1.01), food insecurity rate (OR = 1.21, P = 0.002, 95% CI = 1.07-1.37), number of federally qualified health centers (OR = 1.02, P = 0.028, 95% CI = 1.02-1.08) and per-capita morphine milligram equivalents of hydromorphone (OR = 1.05, P = 0.003, 95% CI = 1.01-1.08) were positively associated with opioid-related mortality.
conclusionsOpioid-related deaths between 2011 and 2014 in the state of Massachusetts appear to be positively associated with the percentage living in poverty, food insecurity rate, number of federally qualified health centers and per-capita morphine milligram equivalents of hydromorphone, but inversely associated with number of social associations per 10 000 and number of hospital beds per 10 000.
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