Evidence map›Paper›PMID 32061006›Full record

ArticleJournal of biomedical materials research. Part A2020

Biodegradable shape memory polymer foams with appropriate thermal properties for hemostatic applications.

Lindy K Jang, Grace K Fletcher, Mary Beth B Monroe, Duncan J Maitland

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. An All-In-One Transient Theranostic Platform for Intelligent Management of Hemorrhage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  5. Article
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lindy K JangDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas.
Grace K FletcherDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas.
Mary Beth B MonroeDepartment of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York.
Duncan J MaitlandDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas.
Texas A&M University · USSyracuse University · US

Funding

Shape Memory Polymer Embolic Foams for Treating Cerebrovascular AneurysmsU01NS089692 · NINDS · TEXAS ENGINEERING EXPERIMENT STATION · PI MAITLAND, DUNCAN J · 2015 to 2018
$2.5M
NINDS NIH HHS U01 NS089692
6 · The paper itself

Abstract

Shape memory polymer (SMP) foams are a promising material for hemostatic dressings due to their biocompatibility, high surface area, excellent shape recovery, and ability to quickly initiate blood clotting. Biodegradable SMP foams could eliminate the need for a secondary removal procedure of hemostatic material from the patients' wound, further facilitating wound healing. In this study, we developed hydrolytically and oxidatively biodegradable SMP foams by reacting polyols (triethanolamine or glycerol) with 6-aminocaproic acid or glycine to generate foaming monomers with degradable ester bonds. These monomers were used in foam synthesis to provide highly crosslinked SMP foam structures. The ester-containing foams showed clinically relevant thermal properties that were comparable to controls and excellent shape recovery within eight min. Triethanolamine-based ester-containing foams showed interconnected porous structure along with increased mechanical strength. Faster hydrolytic and oxidative biodegradation rates were achieved in ester-containing foams in comparison to controls. These biodegradable SMP foams with clinically applicable thermal properties possess great potential as an effective hemostatic device for use in hospitals or on battlefields.

Indexed as

BandagesBiocompatible MaterialsHemostaticsHumansMaterials TestingPolyurethanesPorositySmart MaterialsWound HealingBiocompatible MaterialsHemostaticsPolyurethanesSmart Materialsbiodegradable scaffoldbiomedical devicehemostatpolyurethane foamshape memory polymer

Identifiers

PMID32061006
PMCPMC7364661
OpenAlexW3005913033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.