Evidence map›Paper›PMID 32060901›Full record

ArticleBritish journal of pharmacology2020

Myeloid-specific dopamine D

Xiao Han, Jianbo Ni, Zengkai Wu, Jianghong Wu, Bin Li, Xin Ye, Juanjuan Dai, Congying Chen, Jing Xue, Rong Wan and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  10. Article
  11. The Pivotal Role of Macrophages in the Pathogenesis of Pancreatic Diseases.International journal of molecular sciences · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Anti-Inflammatory Effects of Peripheral Dopamine.International journal of molecular sciences · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Xiao HanDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jianbo NiDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zengkai WuDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jianghong WuDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bin LiDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xin YeDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Juanjuan DaiDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Congying ChenDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jing XueState Key Laboratory of Oncogenes and Related Genes, Stem Cell Research Center, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Rong WanDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li WenDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xingpeng WangDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Guoyong HuDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-3550-6127
Shanghai Jiao Tong University · CN

Funding

National Natural Science Foundation of China 81400663National Natural Science Foundation of China 81570580National Natural Science Foundation of China 81670584National Natural Science Foundation of China 81900584National Natural Science Foundation of China 81900585National Natural Science Foundation of China 81970556Shanghai Pujiang Program 18PJD041Shanghai Pujiang Program 19PJ1408400Shanghai Sailing Program 19YF1438900
6 · The paper itself

Abstract

background and purposeMacrophage infiltration and activation is a critical step during acute pancreatitis (AP). We have shown that pancreas-specific D EXPERIMENTAL APPROACH: Using wild-type and LysM KEY

resultsWe found that dopaminergic system was activated and dopamine reduced inflammatory cytokine expression in M1-polarized macrophages from human PBMCs. Dopaminergic synthesis was also activated, but D CONCLUSION AND IMPLICATIONS: Our data for the first time showed that myeloid-specific D

Indexed as

MacrophagesPancreatitisReceptors, Dopamine D2Acute DiseaseAnimalsDopamineHumansInflammationLeukocytes, MononuclearMiceMice, Inbred C57BLNF-kappa BDopamineDRD2 protein, humanDRD2 protein, mouseNF-kappa BReceptors, Dopamine D2

Identifiers

PMID32060901
PMCPMC7280007
OpenAlexW3005825149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.