Evidence map›Paper›PMID 32060804›Full record

ArticleAging clinical and experimental research2020

Posterior single-stepping thresholds are prospectively related to falls in older women.

Jeremy R Crenshaw, Kathie A Bernhardt, Elizabeth J Atkinson, Sara J Achenbach, Sundeep Khosla, Shreyasee Amin, Kenton R Kaufman

Abstract read
In one paragraph

Article in Aging clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeremy R CrenshawDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Kathie A BernhardtDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Elizabeth J AtkinsonDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Sara J AchenbachDivision of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Sundeep KhoslaDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Shreyasee AminDivision of Rheumatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Kenton R KaufmanDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA. kaufman.kenton@mayo.edu.ORCID http://orcid.org/0000-0002-7311-3781

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
EPIDEMIOLOGY OF AGE-RELATED BONE LOSS, &FRACTURESR01AR027065 · NIAMS · MAYO CLINIC ROCHESTER · PI AMIN, SHREYASEE, KHOSLA, SUNDEEP · 1986 to 2020
$14.9M
MAYO REHABILITATION RESEARCH TRAINING PROGRAMT32HD007447 · NICHD · MAYO CLINIC ROCHESTER · PI BASFORD, JEFFREY R. · 1993 to 2012
$3.1M
National Institutes of Health (US) R01AR027065National Institutes of Health (US) UL1TR000135NCATS NIH HHS UL1 TR000135NIAMS NIH HHS R01 AR027065NICHD NIH HHS T32 HD007447NIH HHS R01AR027065
6 · The paper itself

Abstract

backgroundFalls are a leading cause of injury in older women. Stepping thresholds quantify balance-reaction capabilities. It is unclear how such evaluations predict falls in comparison to, or as a complement to, other objective measures of gait, standing postural control, strength, and balance confidence.

aimsThe objective of this study was to determine if stepping thresholds are prospectively related to falls in older women.

methodsFor this prospective cohort study, 125 ambulatory, community-dwelling women, age ≥ 65 years were recruited. Using a treadmill to deliver perturbations to standing participants, we determined anteroposterior single- and multiple-stepping thresholds. Here, thresholds represent the minimum perturbation magnitudes that consistently evoke one step or multiple steps. In addition, gait kinematics, obstacle-crossing kinematics, standing sway measures, unipedal stance time, the functional reach, lower extremity isometric strength, grip strength, balance confidence, and fall history were evaluated. Falls were prospectively recorded for one year.

resultsSeventy-four participants (59%) fell at least once. Posterior single-stepping thresholds were the only outcome that predicted future fall status (OR = 1.50, 95% CI 1.01-2.28; AUC = .62). A multivariate approach added postural sway with eyes closed as a second predictive variable, although predictive abilities were not meaningfully improved. DISCUSSION: These results align with the previous evidence that reactive balance is a prospective indicator of fall risk. Unlike previous studies, strength scaled to body size did not contribute to fall prediction.

conclusionPosterior single-stepping thresholds held a significant relationship with future fall status. This relationship was independent of, and superior to that of, other measures of standing balance, gait, strength, and balance confidence.

Indexed as

Accidental FallsPostural BalanceAgedAged, 80 and overFemaleGaitHumansIndependent LivingProspective StudiesBalanceBalance reactionsGaitSAFERStanding swayStrength

Identifiers

PMID32060804
PMCPMC7426251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.