Evidence map›Paper›PMID 32060803›Full record

ArticleAging clinical and experimental research2020

Cost trajectories as a measure of functional resilience after hospitalization in older adults.

Cathleen S Colón-Emeric, Jin Huang, Carl F Pieper, Janet Prvu Bettger, David L Roth, Orla C Sheehan

Abstract read
In one paragraph

Article in Aging clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cathleen S Colón-EmericDuke University School of Medicine, Center for the Study of Aging and Human Development, DUMC, Box 3003, Durham, NC, 27710, USA. cathleen.colonemeric@duke.edu.ORCID https://orcid.org/0000-0001-7681-8624
Jin HuangJohns Hopkins University School of Medicine, Center On Aging and Health, Baltimore, MD, 21205, USA.
Carl F PieperDuke University School of Medicine, Center for the Study of Aging and Human Development, DUMC, Box 3003, Durham, NC, 27710, USA.
Janet Prvu BettgerDuke University School of Medicine, Center for the Study of Aging and Human Development, DUMC, Box 3003, Durham, NC, 27710, USA.
David L RothJohns Hopkins University School of Medicine, Center On Aging and Health, Baltimore, MD, 21205, USA.
Orla C SheehanJohns Hopkins University School of Medicine, Center On Aging and Health, Baltimore, MD, 21205, USA.

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Virginia B Kraus · 2006 to 2026
$24.6M
Physical Resiliencies: Indicators and Mechanisms in the Elderly CollaborativeUH3AG056925 · NIA · DUKE UNIVERSITY · PI COLON-EMERIC, CATHLEEN S · 2019 to 2021
$4.6M
Physical Resiliencies: Indicators and Mechanisms in the Elderly CollaborativeUH2AG056925 · NIA · DUKE UNIVERSITY · PI COLON-EMERIC, CATHLEEN S, WHITSON, HEATHER E. · 2017 to 2018
$2.0M
Mentoring Intervention Development in Fall and Fracture PreventionK24AG049077 · NIA · DUKE UNIVERSITY · PI COLON-EMERIC, CATHLEEN S · 2015 to 2019
$361k
NIA NIH HHS K24 AG049077NIA NIH HHS K24 AG049077-01A1NIA NIH HHS P30 AG028716NIA NIH HHS UH2 AG056925NIA NIH HHS UH3 AG056925
6 · The paper itself

Abstract

backgroundAdministrative data sets lack functional measures.

aimWe examined whether trajectories of cost can be used as a marker of functional recovery after hospitalization.

methodsSecondary analysis of the National Health and Aging Trends Study merged with Centers for Medicare and Medicaid Services data. Community-dwelling participants with a first hospitalization occurring after any annual survey were included (N = 937). Monthly total cost trajectories were constructed for the 3 months before and 3 months following hospitalization. Growth mixture models identified groups of patients with similar trajectories. The association of cost classes with five functional outcomes was examined using multivariate models, controlling for pre-hospitalization function and lead time.

resultsFour cost trajectory classes describing common recovery patterns were identified-persistently high, persistently moderate, low-spike-recover, and low variable. Cost class membership was significantly associated with change in Activities of Daily Living (ADL), instrumental ADL, Short Physical Performance Battery, and grip strength (p < 0.005), but not gait speed (p = 0.08). The proportion of patients who maintained or improved SPPB score was 46.8% in the persistently high, 49.2% in the persistently moderate, 52.7% in the low-spike-recover, and 57.2% in the low-variable groups. In models adjusted for known predictors of functional outcome, the magnitude and direction of association was maintained but significance was lost, indicating that cost trajectories' mirror is mediated by predictors of recovery not available in administrative data.

conclusionCost trajectories and total costs are associated with functional recovery following hospitalization in older adults. Cost may be useful as a measure of recovery in administrative data.

Indexed as

Activities of Daily LivingHospitalizationAgedFemaleHumansIndependent LivingMaleMedicareUnited StatesWalking SpeedCostHospitalizationResilienceTrajectory

Identifiers

PMID32060803
PMCPMC7426235

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.