Evidence map›Paper›PMID 32060799›Full record

ArticleEuropean journal of pediatrics2020

Sleep disorders in children and adolescents on regular hemodialysis.

Nevine El-Baroudy, Mona El Falaki, Amal Hagras, Rasha Galal, Radwa Azmy, Basma El-Sayed, Marian Walaan, Happy Sawires

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In one paragraph

Article in European journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nevine El-BaroudyPediatric Department, Cairo University, Cairo, Egypt.
Mona El FalakiPediatric Department, Cairo University, Cairo, Egypt.
Amal HagrasPediatric Nephrology Center, Cairo University, 5 El-Lithy Street El-Maadi El-Gedida, Cairo, 11435, Egypt.
Rasha GalalPediatric Nephrology Center, Cairo University, 5 El-Lithy Street El-Maadi El-Gedida, Cairo, 11435, Egypt.
Radwa AzmyNeurophysiology Department, Cairo University, Cairo, Egypt.
Basma El-SayedNeurophysiology Department, Cairo University, Cairo, Egypt.
Marian WalaanMinistry of Health, Cairo, Egypt.
Happy SawiresPediatric Nephrology Center, Cairo University, 5 El-Lithy Street El-Maadi El-Gedida, Cairo, 11435, Egypt. happy7_kd@yahoo.com.ORCID http://orcid.org/0000-0002-5517-3529
Cairo University · EGMinistry of Health and Population · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disorders in children with chronic kidney disease have been assessed in a limited number of studies. Our aim was to characterize the types of sleep disorders in children on regular hemodialysis and to detect the predictors of sleep efficiency in those children. Forty children and adolescents on regular hemodialysis and another 40 age- and gender-matched control groups were interviewed to answer a questionnaire-based survey, a modified Epworth Sleepiness Scale, to assess excess daytime sleepiness. Also, they underwent an overnight in-laboratory polysomnography to assess total sleep time, sleep efficiency, sleep staging, apnea/hypopnea index, and periodic limb movement index. We found poor sleep efficiency in 20% of cases, and periodic limb movement index higher than 5 in 45%, and apnea/hypopnea index higher than 5 in 40%. There was significant negative correlation between sleep efficiency on one hand, and serum potassium, serum creatinine, and sleep onset on other hand (p < 0.001, p < 0.001, and p < 0.001, respectively). There was significant decrease in hemoglobin, serum iron, and transferrin saturation in patients with excess daytime sleepiness (p < 0.001, p = 0.003, and p = 0.010, respectively). By using multivariate linear regression analysis, we found that serum creatinine was the single independent predictor of sleep efficiency.Conclusion: Poor sleep quality is not uncommon in hemodialysis children. Our results show a lower frequency of sleep disorders in comparison with previous studies. There is a strong association between kidney dysfunction and poor sleep quality in HD children.What is known:• Sleep disturbances can adversely affect a child's daytime performance.• Sleep disorders in children with chronic kidney disease have been assessed in only a limited number of studies.What is new:• Poor sleep quality is not uncommon in hemodialysis children.• There is a strong association between kidney dysfunction and poor sleep quality in hemodialysis children.

Indexed as

Renal DialysisAdolescentCase-Control StudiesChildCross-Sectional StudiesFemaleHumansKidney Failure, ChronicLinear ModelsMaleMultivariate AnalysisPolysomnographyRisk FactorsSleep Wake DisordersAHIHemodialysisPLMISleep efficiencySleep quality

Identifiers

PMID32060799
OpenAlexW3005861371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.