Evidence map›Paper›PMID 32060723›Full record

ArticleWiener klinische Wochenschrift2020

Presepsin:albumin ratio and C-reactive protein:albumin ratio as novel sepsis-based prognostic scores : A retrospective study.

Mustafa Kaplan, Tolga Duzenli, Alpaslan Tanoglu, Basak Cakir Guney, Yesim Onal Tastan, Hatice Selcen Bicer

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Article in Wiener klinische Wochenschrift, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mustafa KaplanDepartment of Internal Medicine, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-0354-4762
Tolga DuzenliDepartment of Gastroenterology, Hitit University Erol Olcok Training and Research Hospital, Corum, Turkey. tolgaduzenli@yahoo.com.ORCID http://orcid.org/0000-0002-6279-1018
Alpaslan TanogluDepartment of Gastroenterology, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-7477-6640
Basak Cakir GuneyDepartment of Internal Medicine, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-2389-2833
Yesim Onal TastanDepartment of Internal Medicine, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-0034-8325
Hatice Selcen BicerDepartment of Internal Medicine, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-6504-3875

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the prognostic value of the presepsin:albumin ratio and C‑reactive protein:albumin ratio in patients with sepsis in the intensive care unit (ICU).

methodsA total of 228 (129 males and 99 females) patients with newly diagnosed sepsis were included in the study. The relationship between the C‑reactive protein:albumin ratio, presepsin:albumin ratio, clinicopathologic parameters, and overall survival were investigated. The associations between C‑reactive protein:albumin ratio and presepsin:albumin ratio were evaluated alongside other inflammation-based prognostic scores such as quick Sepsis Related Organ Failure Assessment (qSOFA).

resultsThe presepsin:albumin ratio was significantly higher in non-survivors (p < 0.01). Patients with a high presepsin:albumin ratio had worse overall survival compared with patients with high C‑reactive protein:albumin ratio levels (p < 0.001).

conclusionPresepsin and presepsin:albumin ratio are markers of adverse prognosis in patients with sepsis and are superior to C‑reactive protein and C‑reactive protein:albumin ratio for this purpose. Presepsin:albumin ratio may be a novel marker of poor prognosis in patients with sepsis in intensive care units.

Indexed as

SepsisAgedAged, 80 and overAlbuminsBiomarkersC-Reactive ProteinFemaleHumansLipopolysaccharide ReceptorsMaleMiddle AgedPeptide FragmentsPrognosisRetrospective StudiesAlbuminsBiomarkersC-Reactive ProteinLipopolysaccharide ReceptorsPeptide Fragmentspresepsin protein, humanAlbuminC‑reactive proteinPresepsinSepsis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.