ArticleCommunications biology2020
High-contrast, synchronous volumetric imaging with selective volume illumination microscopy.
Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 53 citations in OpenAlex.
- Fast 3D dynamic visualization of porcine spermatozoa by using high-resolution wavefront coding light sheet microscopy and machine learning.Scientific reports · 2026Article
- Improved 3D image reconstruction via deep-learning-based fusion of light-field microscopy and Fourier light-field microscopy images.Journal of biomedical optics · 2026Article
- Contributions of Zebrafish to Our Understanding of the Function and Regulation of Sleep.Current sleep medicine reports · 2026Review
- Super Time-Resolved Tomography.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Snapshot 3D at the speed frontier: redefining light-field microscopy for neuroimaging.PhotoniX · 2026Article
- Light-field deep learning enables high-throughput, scattering-mitigated calcium imaging.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Volumetric imaging and computation to explore contractile function in zebrafish hearts.Cell reports methods · 2025Article
- Zebrafish fluorescence imaging platform based on Bessel light sheet illumination.Biomedical optics express · 2025Article
- Volumetric voltage imaging of neuronal populations in the mouse brain by confocal light-field microscopy.Nature methods · 2024Article
- Development of crystal optics for X-ray multi-projection imaging for synchrotron and XFEL sources.Journal of synchrotron radiation · 2024Article
- New opportunities for time-resolved imaging using diffraction-limited storage rings.Journal of synchrotron radiation · 2024Article
- Whole-brain imaging of freely-moving zebrafish.Frontiers in neuroscience · 2023Review
- Volumetric Imaging of Neural Activity by Light Field Microscopy.Neuroscience bulletin · 2022Review
- Light-field microscopy with temporal focusing multiphoton illumination for scanless volumetric bioimaging.Biomedical optics express · 2022Article
- Extended depth-of-field light-sheet microscopy improves imaging of large volumes at high numerical aperture.Applied physics letters · 2022Article
- Comparing synthetic refocusing to deconvolution for the extraction of neuronal calcium transients from light fields.Neurophotonics · 2022Article
- Methods to Evaluate Bacterial Motility and Its Role in Bacterial-Host Interactions.Microorganisms · 2022Review
- Fast whole-brain imaging of seizures in zebrafish larvae by two-photon light-sheet microscopy.Biomedical optics express · 2022Article
- Quantity as a Fish Views It: Behavior and Neurobiology.Frontiers in neuroanatomy · 2022Review
- Neurophotonic tools for microscopic measurements and manipulation: status report.Neurophotonics · 2022Article
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Light-field fluorescence microscopy uniquely provides fast, synchronous volumetric imaging by capturing an extended volume in one snapshot, but often suffers from low contrast due to the background signal generated by its wide-field illumination strategy. We implemented light-field-based selective volume illumination microscopy (SVIM), where illumination is confined to only the volume of interest, removing the background generated from the extraneous sample volume, and dramatically enhancing the image contrast. We demonstrate the capabilities of SVIM by capturing cellular-resolution 3D movies of flowing bacteria in seawater as they colonize their squid symbiotic partner, as well as of the beating heart and brain-wide neural activity in larval zebrafish. These applications demonstrate the breadth of imaging applications that we envision SVIM will enable, in capturing tissue-scale 3D dynamic biological systems at single-cell resolution, fast volumetric rates, and high contrast to reveal the underlying biology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.